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About the Author

Burton Waisbren, MD, FACP, FIDSA has been practicing medicine for over 57 years. He is one of the Founding Members of the Infectious Diseases Society of America (IDSA) and has published research on Lyme disease in prestigious journals such as The Lancet

Dr. Waisbren is a native Milwaukeean who received his B.S. and M.D. degrees from the University of Wisconsin Medical School in Madison, Wisconsin. He served his internship at the Harvard Service at Boston City Hospital. His military service was at the Navy Medical Research Institute, Bethesda, Maryland and the Biological Warfare Center, Camp Detrich, Maryland. 

His residency and fellowship was served at the University of Minnesota Hospitals where he was an instructor in the medical school. He received a master's degree in bacterial genetics from the University of Minnesota in 1951. He moved to Milwaukee, his hometown, in 1951 and established a private practice in internal medicine, infectious disease and immunology. At that time, he also headed the infectious disease control unit at the Milwaukee County Hospital.

From 1951 to 1969, he was the director of the infectious disease division of first the Marquette Medical School and then the Medical College of Wisconsin. During that time, he was appointed associate clinical professor of medicine. He was the medical director of the burn center at St. Mary's Hospital from 1962 to 1982. He has directed a cancer immunotherapy clinic in Milwaukee since 1973. He has published numerous articles in the peer reviewed medical literature and has authored books on systematic methods of critical care and on medical emergencies. 

Dr. Waisbren is board-certified by the American Board of Internal Medicine and also is a fellow of the American College of Physicians and the Infectious Disease Society of America. He is a founding member of the Infectious Disease Society of America, the American Burn Association, and the Critical Care Society of America. 



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Book Review by  Bryan Rosner, author of The Top 10 Lyme Disease Treatments: "This is the book the Lyme disease community has been waiting for. This author's credibility will finally lend credence to the reality of chronic Lyme disease. This book will open doors for Lyme disease patients, doctors and researchers for decades to come." 




If you would like to educate your family, friends, or local doctor on the reality of chronic Lyme disease, this book would make the perfect gift! Dr. Waisbren's experience and credibility have never before been available to the Lyme disease community! Visit our wholesale ordering page to buy copies, today! 




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          Paperback Book • $24.95View the Back Cover

          Written by Burton Waisbren, MD, FACP, F-IDSA

          Published in January, 2012

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          Visit Dr. Waisbren's Clinic Website.

Paperback Book, $24.95

Published in January, 2012

Could this be the most important Lyme disease book ever published? 

Join Dr. Burton Waisbren on a journey of discovery through 51 cases of chronic Lyme disease which he personally treated, and essays in their regard. Draw from his vast wisdom as a physician who began to practice medicine over 57 years ago, in 1951, and find out which treatments he is using to help his numerous, current chronic Lyme disease patients.

Many people are saying that this is the most important Lyme disease book ever written! Keep reading to find out why...

One of the biggest obstacles facing patients with chronic Lyme disease is the IDSA (Infectious Diseases Society of America). This prestigious organization has denied the scientific validity of chronic Lyme disease and looks down upon the Lyme-literate physicians who treat it.

The author of this book is not just any Lyme disease doctor!

Dr. Burton Waisbren (clinic website) is not only a current Fellow of the IDSA, he is is also one of its Founding Members! He has been in medical practice for over 57 years and has published Lyme disease research in prestigious journals, including The Lancet. In this book, he tells us the truth: that chronic Lyme disease is a real medical condition which he has treated dozens of times in his 57+ year career as an infectious disease physician. 

By reading this book, you will find out how Dr. Waisbren is helping his patients and which treatments he has found to be most effective for chronic Lyme disease.

Why is this such an important book? Never before has there been a Lyme disease author with the credentials and authority of Dr. Burton Waisbren. 

What's Inside The Book?

  • Which antibiotics and combinations of antibiotics Dr. Waisbren uses with his patients.

  • Dr. Waisbren's theories on chronic Lyme disease and related medical conditions such as ALS, Multiple Sclerosis, and others.

  • Mirco-organisms involved in chronic Lyme disease and their antimicrobial susceptibilities, including Bartonella, Babesia, Ehrlichia, and others.

  • The use of Gamma Globulin in the treatment of chronic Lyme disease

  • The kinds of studies that are desperately needed for more understanding of chronic Lyme disease

  • IV vs. oral antibiotics

  • Lyme disease testing methods

  • Dr. Waisbren's experience treating Bartonella and various novel approaches to managing it, with references to international Bartonella studies 

  • Many more topics!

Video Book Review by Bryan Rosner

Table of Contents



Observations That Surfaced in the Author’s Study of Chronic Lyme Disease since 1989 

Definition of Chronic Lyme Disease Syndrome 

Part 1: Fifty-One Consecutive Case Reports of Patients Seen between 2007 and 2011 by Dr. Waisbren 

Part 2: Essays Regarding Chronic Lyme Disease Syndrome 

Essay 1: A War against Ticks as a Means to Prevent Lyme Disease 

Essay 2: Problems Inherent in the Development of a Lyme Vaccine and the Wide Implication of These Problems 

Essay 3: Testimony regarding Viral Vaccines and Their Dangers, Given by Dr. Burton Waisbren before Congress in 1999 

Essay 4: The “Emperor’s New Clothes Syndrome,” Chronic Lyme Disease, and the Infectious Disease Society of America (IDSA) 

Essay 5: Microorganisms Involved in Chronic Lyme Disease and Their Antimicrobial Sensitivities 

Essay 6: A Suggestion That It Might Be Worthwhile to Add Gamma Globulin to Treatment Protocols for Chronic Lyme Disease 

Essay 7: The Treatment of Amyotrophic Lateral Sclerosis with Anti-Lyme Antibiotics 

Essay 8: A Consideration of the Laboratory Diagnosis of Chronic Lyme Disease—Comments about the Western Blot Method 

Essay 9: Experimental Studies “Begging” to be Done regarding Lyme Disease

Essay 10: Two Protocols to Be Considered for the Treatment of Chronic Lyme Disease Syndrome 

Essay 11: Further Consideration of Demyelination (Multiple Sclerosis) and the Chronic Lyme Disease Syndrome 

Part 3: Additional References upon Which Many of the Observations and Suggestions in This Book Are Based

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The reader may wonder how a practicing physician from Milwaukee has chosen to present fifty-one case reports and eleven essays regarding his treatment of chronic Lyme disease.

My involvement with Lyme disease started in 1989, when the son of a woman who was dying from amyotrophic lateral sclerosis (ALS) called me and suggested that his mother’s illness may have started when she developed a severe case of Lyme disease.

Intrigued by his question, I investigated by having a study done by a professor of neurology at the medical school in Madison, Wisconsin, using sera that had been collected from a number of patients who had ALS. Enough of the sera showed antibodies to Borrelia burgdorferi to suggest that a relationship between ALS and Lyme disease may be present. We reported this finding in the medical journal The Lancet.1 This awakened my interest in Lyme disease, and I saw my first case in 1990.

One thing led to another, and through word of mouth and sharing my experiences on my website, I began to see patients with chronic Lyme disease and to study this disease. By 2007, I was seeing patients with this disease on a regular basis, and this has continued to occur to the present. 

To my wonderment, literature began to appear, written by some of my respected colleagues, that in a sense denied that the syndrome of chronic Lyme disease occurs (see essay 4 in this book). Accordingly, I felt that the time had come to share my experience with this syndrome with my colleagues and with individuals who are unfortunate enough to have chronic Lyme disease. 

This book is based on my experiences in the practice of what I had termed “investigative internal medicine” for greater than fifty-five years and my teaching of medical infectious diseases, first at Marquette University Medical School and then at the Medical College of Wisconsin, between 1952 and 1990.4 Based on my initial training in infectious diseases, the medical literature, and my clinical experience, I have come to the conclusion that there is an epidemic of chronic Lyme disease occurring in the United States that warrants more attention than it is getting from the government and the academic medical establishment. It is hard for me to believe that the fifty-one cases of what I call the chronic Lyme disease syndrome represent a figment of my imagination. It will be up to the reader to make a decision in this regard. 

I suggest that those who doubt that the Lyme disease syndrome exists and that it can be treated turn to the over two hundred peer-reviewed references included in summary articles written by two giants in the Lyme disease field: Dr. B. A. Fallon and Dr. Steven Phillips.2, 3 


  1. B. A. Waisbren, N. Cashman, R. F. Schell, and R. Johnson, “Borrelia Burgdorferi Antibodies in Amyotrophic Lateral Sclerosis,” The Lancet 8:2 (8554) (1987): 332–333. 

  2. B. A. Fallon, J. A. Niedls, “Lyme Disease, a Neuropsychiatric Disease,” American Journal of Psychiatry 151 (1994): 1571–1580. 

  3. Dr. Steven Phillips, “Chronic Lyme–An Evidence-Based Review,” (May 2008). http://www.ilads.org/lyme_research/chronic_lyme.html  

  4. B. A. Waisbren, Adventures in the Practice of Investigative Internal Medicine, 1951–2006, ISBN 798-1-4251-1328-5.


Observations That Surfaced in the Author’s
Study of Chronic Lyme Disease Since 1989

  1. Chronic Lyme disease does exist. It would be hard to conclude that these patients and the many others of their ilk that the author has seen are just figments of his imagination. 

  2. The number of unsuccessful doctor-patient relationships experienced by the patients in these case reports suggests that an epidemic of chronic Lyme disease may be occurring in this country and that it deserves more attention by the medical profession and public than it is receiving. 

  3. Some patients with the chronic Lyme disease syndrome may be helped by the treatment of the organisms known to be involved and by treatment of autoimmune complications, as they have been discussed in this series of essays.

Definition of Chronic Lyme Disease Syndrome

Adhering to the “Socratic” method, we will start with the definition of the chronic Lyme disease syndrome as it is used in this book. Chronic Lyme disease is an emerging infectious disease caused by at least three species of bacteria belonging to the genus Borrelia. The disease is named after the town of Lyme, Connecticut, where a number of cases were identified in 1975. 

Chronic Lyme disease syndrome is suffered by some individuals who have been bitten by ticks and have not responded to the results of the bite by a twenty-four day course of oral doxycycline. 

The syndrome has many aspects, and some of its sufferers have excessive fatigue, joint and muscle pains and aches, “brain fog,” skin rashes, demyelinating signs, and symptoms of gastrointestinal dysfunction. Usually more than one microorganism is involved, and in some cases, autoimmunity occurs as manifested by multiple-sclerosis-like signs. 

Duration of this syndrome, if untreated, may be months and even years, during which time a patient may be seriously and permanently debilitated.


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