Archive for November, 2011

Linda’s  comment:  Lyme neuroborreliosis (LNB) is the most frequent tick-borne infectious disease of the central nervous system. In acute LNB and the rare **chronic state of infection**, patients can experience cognitive deficits such as attention and memory disturbances.

Continuous exposure to intrathecal B. burgdorferi OspC
led to activation of microglia and axonal damage without demonstrable
cognitive impairment in experimental mice. These results suggest that
long-term intrathecal exposure to OspC resulted in axonal damage that
may underlie the neurologic manifestations in chronic LNB.

Linda’s comment:  We previously observed that γδ T cells in vitro are activated by Borrelia burgdorferi in a TLR2-dependent manner. We now observe that the activated γδ T cells can in turn stimulate dendritic cells in vitro to produce cytokines and chemokines that are important for the adaptive immune response.

 This paralleled greater Borreli a burden in
γδ-deficient mice as well as more cardiac inflammation. These findings
are consistent with a model of γδ T cells functioning to promote the
adaptive immune response during infection.

Linda’s comment: Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi.

CONCLUSION: Antibiotics have varying effects on the different
morphological forms of B. burgdorferi. Persistence of viable organisms
in round body forms and biofilm-like colonies may explain treatment
failure and persistent symptoms following antibiotic therapy of Lyme
disease.

Linda’s Comment:   Bell’s palsy and Lyme neuroborreliosis are the two most common diagnoses in patients with peripheral facial palsy in areas endemic for Borrelia burgdorferi.\

Excerpt:

CONCLUSIONS: We found that the time of the year, associated neurological
symptoms and mononuclear pleocytosis were strong predictive factors for
Lyme neuroborreliosis as a cause of peripheral facial palsy in an area
endemic for Borrelia.

Linda’s comment; Historically, flea-borne diseases are among the most important medical diseases of humans. Plague and murine typhus are known for centuries while the last years brought some new flea-transmitted pathogens, like R. felis and Bartonella henselae.

Excerpt:

ABSTRACT: Historically, flea-borne diseases are among the most important
medical diseases of humans. Plague and murine typhus are known for
centuries while the last years brought some new flea-transmitted
pathogens, like R. felis and Bartonella henselae.

Linda’s comment  Reversible dementias are rare and account for approximately 1.5% of all dementias. The most frequent etiology is represented by neurosurgical causes such as benign tumours, adult chronic hydrocephalus (so-called « normal pressure » hydrocephalus) or subdural hematoma, which are easily revealed by neuroimaging.

Link: http://www.medfetch.com/r/39715/21690030/

Excerpt:

Reversible dementias are rare and account for approximately 1.5% of all
dementias. The most frequent etiology is represented by neurosurgical
causes such as benign tumours, adult chronic hydrocephalus (so-called
« normal pressure » hydrocephalus) or subdural hematoma, which are
easily revealed by neuroimaging.

See ALL of Dr. Gordon’s PEMF studies and information:

http://gordonresearch.com/articles_PEMF/

Link: http://www.resultsrna.com/research/acs_200_borrelia_kill_time_study.php

Excerpt:

The purpose of this study was to estimate the antimicrobial activity of ACS 200 test formulation on Borrelia burgdorferi. Since there is no current protocol for disinfectant testing with Borrelia burgdorfer, and since this organism does not form colonies on agar, loss of motility observed through dark field microscopy was used to determine the extent of kill.