antioxidants – F.I.G.H.T for your health! http://lymebook.com/fight Linda Heming describes her Lyme disease healing journey Wed, 06 Nov 2013 05:54:37 +0000 en-US hourly 1 https://wordpress.org/?v=4.9.25 Vitamin C – with comments from Linda & Dr. Gordon http://lymebook.com/fight/vitamin-c-with-comments-from-linda-dr-gordon/ http://lymebook.com/fight/vitamin-c-with-comments-from-linda-dr-gordon/#respond Thu, 24 Mar 2011 04:40:27 +0000 http://lymebook.com/fight/?p=2292 Linda’s comments: Well I would blow their boxers off…I take 16,000 to 24,000 daily of the BioEnergyC from www.longevityplus.com My dogs get a minimum of 4000 mg in a one gallon water bowl….the five gallon water dish gets 20,000 mgs. I quiet frankly sick and tired of hearing the NIH and FDA and the pharmaceuticals squawk about taking high dosing of VitC….poor fellows, don’t have a clue…

Dr. Gordon’s Comments:

Everything  you think you know about vitamin C is probably more than 50% wrong  and, if you relied on this official appearing document re vitamin C, you would not use it.  The attached document is from NIH so it gives you all the negative but you must know all that too.

But I am providing you with the contrary opinion. You will be amazed at how the right hand of the government does not know what the left hand is doing! FDA has approved vitamin C for treating one type of cancer!  That opens the door to great speculation and further research about non-toxic cancer therapies and I am excited to incorporate into this program the power of PEMF, which makes each cell ALKALINE and restores transmembrane potential. So I believe I have two or more non-toxic approaches that need to be looked at concurrently and incorporated with my FIGHT program for long term success.

Using IV VIT C with  my FIGHT program and PEMF ( Pulsed Electromagnetic  Field Therapy )  you will see and feel results  with PEMF on top of my FIGHT program, I am clearly  getting younger!

There are other ways to enhance the effectiveness of high dose IV Vitamin C in treating cancer and using it alone I do not find that IV VIT C is very often curative but it almost always helps and buys time for other therapies to be instituted.

Remember   we all need to improve outcomes, as our patients pay cash. We are not endowed by Government funds like our brethren using their chemo/radiation.  They are generally covered and   just bill the system and are ok no matter what the outcome.  We are NOT OK unless we turn out superior results and have data that shows we can beat mainstream outcomes hands down.

This NIH authoritative appearing well– referenced document would make anyone think oral low dose (2000 mg and under) Vitamin C is dangerous and causes cancer and heart disease. It appears to be fully referenced up to date through November 2009 yet it is missing an important point; somehow IV vitamin C WITH K-3 is now FDA approved for treating bladder cancer!! After all if anyone knew that vitamin C could be FDA approved for one cancer then some doctors would have some interest in trying it in other cancers just like the oncologists do everyday.

How can I and many of our colleagues be successfully using oral and IV vitamin C to keep Cancer patients alive far longer than their oncologists predict and still be considered by mainstream oncologists to be so wrong?  They tell their patients to never use vitamin C!

This report even has recommendations about not exceeding what they have established now, as their safe upper limit of oral vitamin C at 2000 mg MAX. Yet it is hard for them to ignore entirely what we are doing with cancer so they throw in some words to try to sound plausible with their otherwise very negative review of vitamin C. This is BURIED in the attached report but of course they have their numbers about what the maximum serum levels achievable with oral vitamin c vs.  the high serum levels achievable with IV Vitamin C. Those that are interested to get to the bottom of this mystery will find that vitamin c deserves your serious attention, IV and ORAL because there is always the rest of the story.

This is just one paragraph from many articles you may want to review once you read my comments: ’The bottom line is: Apatone selectively targets and kills tumor cells using non-toxic biochemistry that protects surrounding healthy tissue.” Licensed in 2004 to IC-MedTech, Inc., a California-based biotechnology company, the first clinical trial began in 2005 to evaluate the drug in prostate cancer patients. The clinical studies, which were conducted at Summa Health System in Akron, Ohio and with Dr. Ananias Diokno at William Beaumont Hospital in Royal Oak, Mich., examined the safety and effectiveness in 17 end-stage prostate cancer patients for 12 weeks. These patients took Apatone orally each day. The trials were supported by the Beaumont Foundation, Summa Health System and IC-MedTech.

Yet this is the best that the NIH report can offer the informed patients and physicians trying to help cancer patients. They admit there could be some discrepancy in the research but clearly tell no one that vitamin C is working when mixed with the correct form of vitamin K-3 (Apatone), which increases its oxidative capacity.

Remember this  work using vitamin C  for cancer  goes back several years now  and it consists IV vitamin C with the correct form of vitamin K, which unfortunately it appears that  most physicians  have never found  the correct form since there appears to be as many as 6 molecules being sold as vitamin K-3 and some are toxic. Yet in the lecture I will deliver for The Oxidative Training Workshop during IMOSAIC on April 7th at the Minneapolis conference, sponsored by ACAM, AHIMA, AAEM and ICIM, I will educate you about how easily you can kill the therapeutic effect when you are trying to master oxidative therapies with something as simple as giving NAC or GLUTATHIONE concurrently.

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Link: http://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/

Excerpt:

Introduction
Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement. Humans, unlike most animals, are unable to synthesize vitamin C endogenously, so it is an essential dietary component [1].

Vitamin C is required for the biosynthesis of collagen, L-carnitine, and certain neurotransmitters; vitamin C is also involved in protein metabolism [1,2]. Collagen is an essential component of connective tissue, which plays a vital role in wound healing. Vitamin C is also an important physiological antioxidant [3] and has been shown to regenerate other antioxidants within the body, including alpha-tocopherol (vitamin E) [4]. Ongoing research is examining whether vitamin C, by limiting the damaging effects of free radicals through its antioxidant activity, might help prevent or delay the development of certain cancers, cardiovascular disease, and other diseases in which oxidative stress plays a causal role. In addition to its biosynthetic and antioxidant functions, vitamin C plays an important role in immune function [4] and improves the absorption of nonheme iron [5], the form of iron present in plant-based foods. Insufficient vitamin C intake causes scurvy, which is characterized by fatigue or lassitude, widespread connective tissue weakness, and capillary fragility [1,2,4,6-9].

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CANCER’S WORST ENEMY & Charles B. Simone (with comments from Dr. Gordon) http://lymebook.com/fight/cancers-worst-enemy-charles-b-simone-with-comments-from-dr-gordon/ http://lymebook.com/fight/cancers-worst-enemy-charles-b-simone-with-comments-from-dr-gordon/#comments Thu, 04 Nov 2010 06:26:12 +0000 http://lymebook.com/fight/?p=1842 This is all fact; Dr Simone is the real thing! It’s almost unheard of, an oncologist who works with the body. The attorney writing this our friend, yours and mine, as he regularly beats FDA when they try to take away all of our supplements.  

These are our kind of heroes. 

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com
____________________________________

CANCER’S WORST ENEMY
By Attorney Jonathan Emord
Author of “The Rise of Tyranny”
July 26, 2010
NewsWithViews.com

The worst enemy cancer has is not some chemotherapy admixture, it is not surgery, and it is not radiation treatment. The worst enemy cancer has comes in the form of a brilliant, soft spoken internist, oncologist and immunologist in Lawrenceville, New Jersey. He is Dr. Charles B. Simone of the Simone Protective Cancer Center, author of Cancer and Nutrition: A Ten Point Plan to Reduce Your Chances of Getting Cancer (1982) and many other remarkable books on preventing and treating cancer. 

This gentle, unassuming man, approachable by everyone and possessed of an affable and compassionate manner, has prolonged the life of many cancer patients-long past the time their attending physicians thought possible. As he told me many years ago, when there is no known cure, you do not do everything imaginable to kill the cancer and thereby kill the patient, you do everything imaginable to manage the cancer and extend the life of the patient. In short, while many oncologists view incurable cancers as diseases to be conquered in which either the patient or the cancer will win (with the cancer almost always winning), Dr. Simone views incurable cancers as diseases to be managed for a lifetime (with the patient living to the maximum extent possible). Dr. Simone wants his patients to live with cancer, not die from it or from cancer treatment. He aims to give his patients longevity and quality of life.

This remarkable physician is known to Presidents, members of Congress, celebrities, and moguls worldwide, but comes from humble origins. Chuck Simone was the son of an auto mechanic. Chuck paid his way through eight years at the university, working 24 to 30 hours each weekend in the laboratory of a hospital. He was driven to become a physician from his earliest days, and he set out to achieve that mission without the slightest fear of obstacles, financial or academic. He graduated from Rutgers with highest honors (a B.S. in biological sciences) and then from Rutgers College of Medicine. He also earned the rare Masters of Medical Science degree from Rutgers while investigating the cancer killing properties of plant herbals. He trained in Internal Medicine at the Cleveland Clinic. He thereafter worked in the Immunology Branch and Medicine Branch and the Pharmacology Branch and Medicine Branch at the National Cancer Institute, National Institutes of Health in Bethesda. He was an Associate Professor in the Department of Radiation Oncology and Nuclear Medicine at Thomas Jefferson University, Philadelphia, and since 1988, has been the Director of his own remarkable cancer clinic, the Simone Protective Cancer Center. 
While at NCI, he made critical scientific discoveries on the properties in the human anatomy responsible for killing aberrant cells. He uncovered the fundamental mechanism of how human white cells kill foreign cells. He helped demonstrate how “complement proteins” aid in killing. He demonstrated how adriamycin, an anti-cancer drug, operates at the cellular level. He conceived and developed the idea of splicing monoclonal antibodies to killing cells that seek out cancer cells, called directed effector cell killing.

Dr. Simone has quietly gained an international reputation, drawing people from all walks of life to his clinic. Among them are leading politicians, actors, actresses, and entrepreneurs. For example, he treated Michael Landon and Vice President Hubert Humphrey. He advised President Reagan on nutritional means to reduce the risk of cancer. When conventional methods fail, frequently word comes of Dr. Simone, and he arrives to improve the quality of care and the chance for greater life.

Dr. Simone was among the first to comprehend the significance of antioxidants and other nutrients in the treatment of cancer and has debunked the myth that nutrients reduce the effectiveness, or interfere with, conventional chemotherapy and radiation. To the contrary, he has shown that those therapies are improved in their effectiveness and patients are better able to endure them when nutritional therapy is used. 

He first discovered the association of nutrition and cancer when treating Vice President Humphrey in the late 1970’s. Through scientific research and medical practice, Dr. Simone came to find nutritional therapy, lifestyle modification, and exercise critical in the management of almost all cancers. In 1982 he published the definitive Cancer and Nutrition. In 1980 he founded the KidStart Prevention Program where he works with inner city churches to teach children nutrition and lifestyle habits that can reduce their risk of contracting cancer as well as means to detect and treat cancer.

Dr. Simone has designed nutritional formulations to improve hydration in athletes and in combat troops, including his Super Energy, hydration formula, proved effective in actual combat conditions in the Middle East. He now works with NCI on research that will lead to cancer detection as much as two years earlier than is presently possible. His research is showing that proteomic patterns can reveal cancer much earlier than present techniques of diagnosis.

My knowledge of Dr. Simone is far from simply academic, it is personal. My mother, Jeanette Emord, was diagnosed with chronic lymphocytic leukemia in 1984 at the age of 57. Her attending oncologist advised her coldly that she could expect to live approximately five years past that date of diagnosis. With that death sentence, she like most cancer patients presumed there was nothing that could be done to alter the timeline. 

To be fair, everyone diagnosed with the same disease in her treatment group who followed the standard chemotherapy died within five years of diagnosis. But thanks to Dr. Simone, my mother escaped that fate. She lived and lived well, to the age of 83. Repeatedly during her illness, conventional physicians would recommend a specific course of treatment or would send her home presuming death imminent, and Dr. Simone would intervene, correcting the errors and restoring her to health. He saved my mother’s life no fewer than four times. In each instance, had the advice of attending physicians been followed, she would have died at a much earlier age. It remains the case that the choice of physician often determines the outcome of each struggle with terminal illness.

Under Dr. Simone’s constant care through the years my mother, a genius who loved life and contributed selflessly to the lives of others, enjoyed a high quality of life. That was made possible because of a physician tirelessly dedicated to service, driven by a love of humanity and an intense desire to make a difference in each life that comes before him. On behalf of all who have overcome a medical death sentence thanks to the extraordinary interventions of Dr. Simone, I say thank you. 

© 2010 Jonathan W. Emord – All Rights Reserved
Jonathan W. Emord is an attorney who practices constitutional and administrative law before the federal courts and agencies. Congressman Ron Paul calls Jonathan “a hero of the health freedom revolution” and says “all freedom-loving Americans are in [his] debt . . . for his courtroom [victories] on behalf of health freedom.” He has defeated the FDA in federal court a remarkable seven times, six on First Amendment grounds, and is the author of Amazon bestsellers The Rise of Tyranny, and Global Censorship of Health Information. 
For more info visit Emord.com.
Website: Emord.com
E-Mail: jwemord@gmail.com

Charles B. Simone, M.MS., M.D.

Charles B. Simone, M.MS., M.D. is an Internist (Cleveland Clinic 1975-77), Medical Oncologist (National Cancer Institute 1977-82), Tumor Immunologist (NCI 1977-82), and Radiation Oncologist (University of Pennsylvania 1982-85), and is the Founder of the Simone Protective Cancer Institute (1980).  He wrote Cancer and Nutrition (1981, third revision 2005), The Truth About Breast Health – Breast Cancer (2002), The Truth About Prostate Health – Prostate Cancer (2005), How To Save Yourself From A Terrorist Attack (2001), Nutritional Hydration, Medical Strategy for Military and Athlete Warriors (2008), helped organize the Office of Alternative Medicine, NIH (1992), helped write the Dietary Supplement, Health and Education Act of 1994, helped win landmark cases against the FDA by showing they violated the First and Fifth Amendment rights of Americans, helped introduce the Health Freedom Protection Act of 2005 (H.R. 2117), was bestowed the first Bulwark of Liberty Award in 2001 by the American Preventive Association and the James Lind Scientific Achievement Award in 2004, and continues bench research with the NCI showing that proteomic patterns can diagnose specific cancers at earlier stages than we are currently able to do (Lancet Feb 2002, JNCI Nov 2002), as well as clinical research that shows in 61 human studies Antioxidants and Other Nutrients Do Not Interfere with Chemotherapy or Radiation, and Can Increase Kill, Decrease Side Effects, and Increase Survival (Altern Ther Health Med. 2007. 13(1):22-28; and 13(2):40-46; JNCI Nov 2008).  

     In 1980 Dr Simone founded the Simone KidStart Prevention Program, the first of its kind.  Since 1980 he has worked with inner city churches to teach prevention, detection, and treatment. He is a consultant for heads of state of the US and other countries, celebrities, and advises many governments regarding health care. He testifies for the Senate and House on matters concerning health, cancer, disease prevention, children’s health programs, FDA reform, and alternative medicine. He appears on 60 MINUTES, Prime Time Live, Fox News Channel, and others.

     Dr Simone coaches some world-class elite endurance athletes, such as Khalid Khannouchi (“Greatest marathoner ever” USA Today Nov 2008), some Gold Medal Olympians, and others.  He developed the patented Nutritional Hydration formula (Simone Super Energy) that was first used in desert warfare in 1990, worked closely with Special Operations Forces, and in December 2003 was presented with the Distinguished Speaker Award at the Special Operations Medical Conference in Tampa, FL.  Dr Simone is currently working to improve combat effectiveness using nutritional hydration for the Air Force Special Operations Command at Hurlburt Field, FL.

Simone Protective Cancer Center
123 Franklin Corner Rd.
Lawrenceville, NJ 08648 
609-896-2646 
http://www.DrSimone.com 
http://www.PrincetonInstitute.com 
http://www.NutritionalHydration.com
http://www.SimoneProtectiveHealth.com
http://www.SimoneSuperEnergy.com
http://www.StopFDACensorship.org

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Organic produce is nutritionally superior to so-called “conventional” produce http://lymebook.com/fight/organic-produce-is-nutritionally-superior-to-so-called-conventional-produce/ http://lymebook.com/fight/organic-produce-is-nutritionally-superior-to-so-called-conventional-produce/#respond Mon, 01 Mar 2010 06:59:38 +0000 http://lymebook.com/fight/?p=887  Linda’s comments:  This is a great article on how to purchase organic produce and why it is important to do your best to eat organic.  I’m sure you have seen these BIG wooden tubs that folks use to plant flowers in?  These are perfect for your patio to plant your own organic produce, plus it isn’t on the ground to break your back bending over weeding, and feeding your plants…..I use chicken wire to protect it from rabbits, etc.  Zip ties are great for hooking it around the planter….Find your local organic farmers.  They are popping up all over Arizona, plus the Farmers Markets are growing like wild fire….

Full article: http://www.naturalnews.com/027854_organic_food_nutrition.html

Excerpt:

NaturalNews) Organic produce is nutritionally superior to so-called “conventional” produce, according to a comprehensive review conducted by researchers from the University of Aix-Marseille for the French food agency (AFSSA) and published in the journal Agronomy for Sustainable Development.

“This critical literature review indicates that organic agriculture, as developed until now, has the potential to produce high-quality products with some relevant improvements in terms of anti-oxidant phytomicronutrients, nitrate accumulation in vegetables and toxic residue levels,” the researchers wrote.

To be recognized as “organic,” a food product must be produced without the use of genetic modification or chemical fertilizers or pesticides, and must promote sustainable cropping methods. In the United States, organically produced meat and dairy must be raised without the use of synthetic growth hormones or antibiotics. Hormones and antibiotics are banned in animal production across the board in the European Union.

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VITAMIN C AND ACIDITY http://lymebook.com/fight/vitamin-c-and-acidity/ http://lymebook.com/fight/vitamin-c-and-acidity/#respond Mon, 25 Jan 2010 01:49:42 +0000 http://lymebook.com/fight/?p=785 Excerpt:

(OMNS, December 8, 2009) Vitamin C is commonly taken in large quantities to improve health and prevent asthma, allergies, viral infection, and heart disease [1,2]. It is non-toxic and non-immunogenic, and does not irritate the stomach as drugs like aspirin can. Yet vitamin C (L-ascorbic acid) is acidic. So, a common question is, what are the effects from taking large quantities?

Ascorbic acid is a weak acid (pKa= 4.2) [3], only slightly stronger than vinegar. When dissolved in water, vitamin C is sour but less so than citric acid found in lemons and limes. Can large quantities of a weak acid such as ascorbate cause problems in the body? The answer is, sometimes, in some situations. However, with some simple precautions they can be avoided.

Acid in the Mouth
First of all, any acid can etch the surfaces of your teeth. This is the reason the dentist cleans your teeth and warns about plaque, for acid generated by bacteria in the mouth can etch your teeth to cause cavities. Cola soft drinks contain phosphoric acid, actually used by dentists to etch teeth before tooth sealants are applied. Like soft drinks, ascorbic acid will not cause etching of teeth if only briefly present. Often, vitamin C tablets are coated with a tableting ingredient such as magnesium stearate which prevents the ascorbate from dissolving immediately. Swallowing a vitamin C tablet without chewing it prevents its acid from harming tooth enamel.

Full article: http://www.orthomolecular.org

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High Fructose Intake Correlated With High Blood Pressure http://lymebook.com/fight/high-fructose-intake-correlated-with-high-blood-pressure-2/ http://lymebook.com/fight/high-fructose-intake-correlated-with-high-blood-pressure-2/#respond Sun, 06 Dec 2009 04:36:22 +0000 http://lymebook.com/fight/?p=627 TAGS: h

Norra MacReady

Authors and Disclosures

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INFORMATION FROM INDUSTRY
When initial antihypertensive therapy isn’t enough…
What will your patients need from their next-add on?
Explore this treatment optionNovember 4, 2009 (San Diego, California) – High fructose consumption is independently associated with high blood pressure, according to findings presented here at Renal Week 2009: American Society of Nephrology 2009 Annual Meeting.

An analysis of data from more than 4500 participants in the National Health and Nutrition Examination Survey (NHANES) showed that consuming 74 grams or more of fructose per day – equivalent to about 2.5 12-ounce cans of sugary soda – correlated significantly with blood pressure of at least 135/85 mm Hg; the relation grew stronger as blood pressure rose. The survey participants had no history of hypertension.

Fructose consumption, in the form of added sugar, has been rising in Western nations since the 1900s, and parallels the growing prevalence of hypertension, said lead investigator Diana I. Jalal, MD, assistant professor of renal medicine at the University of Colorado Health Sciences Center in Aurora.

To examine the relation between the 2, she and her colleagues used the NHANES data to evaluate median fructose intake from food high in added sugar, including bakery products, dairy desserts, chocolate and other candy, dried fruits, honeys, jams, jellies, syrups, and sugar-sweetened soft drinks. Soft drinks alone account for 33% to 40% of fructose consumption in the United States, Dr. Jalal noted.

Fresh fruits were excluded from the analysis because they contain ascorbate, antioxidants, and potassium, which counteract the effect of fructose, Dr. Jalal said during her presentation. Using responses on self-administered dietary questionnaires, the investigators calculated median fructose intake of the participants to be 74 g/day. They then studied the relation between fructose consumption and blood pressure, adjusting for demographics, physical activity, other dietary factors, cardiovascular risk factors, and findings on laboratory tests. Data from 4528 adults were included in the analysis.

Daily fructose consumption of 74 g or more was independently associated with a 28% increased risk for blood pressure of 135/85 mm Hg or higher, a 36% increased risk for blood pressure of140/90 mm Hg or higher, and an 87% increased risk for blood pressure of 160/100 mm Hg or higher.

The relation was seen only between systolic blood pressure and fructose intake, Dr. Jalal said. There was no correlation between fructose consumption and diastolic blood pressure.

“In subjects with no history of hypertension, there is an independent and significant graded association between high fructose intake and systolic blood pressure levels,” she concluded. The mechanism underlying the relation is unclear.

Among other variables, black ethnicity and waist circumference were significantly associated with higher levels of fructose intake, independent of calorie or carbohydrate consumption. Inverse correlations were seen for sodium and alcohol consumption and fructose. “It seems that people either like their alcohol or they like their sugar, and they like their salt or they like their sugar,” Dr. Jalal told Medscape Nephrology.

This study shows that “we must pay more attention to the nutritional needs of our patients,” said Talal Ikizler, MD, associate professor of medicine at Vanderbilt University, and medical director of the Vanderbilt University Outpatient Dialysis Unit in Nashville, Tennessee.

Nephrologists rarely catch patients at the early stages of renal disease, when risk factor modification might still be possible, explained Dr. Ikizler, who was not involved in this research. However, internists and other primary care physicians do have these opportunities. Whenever possible, patients should be “warned of the consequences of their dietary choices early on.”

Dr. Jalal and Dr. Ikizler have disclosed no relevant financial relationships.

Renal Week 2009: American Society of Nephrology (ASN) 2009 Annual Meeting: Abstract TH-FC037. Presented October 29, 2009.

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High Fructose Intake Correlated With High Blood Pressure http://lymebook.com/fight/high-fructose-intake-correlated-with-high-blood-pressure/ http://lymebook.com/fight/high-fructose-intake-correlated-with-high-blood-pressure/#respond Tue, 10 Nov 2009 17:39:28 +0000 http://lymebook.com/fight/?p=400 By Norra MacReady

November 4, 2009 (San Diego, California) — High fructose consumption is independently associated with high blood pressure, according to findings presented here at Renal Week 2009: American Society of Nephrology 2009 Annual Meeting.

An analysis of data from more than 4500 participants in the National Health and Nutrition Examination Survey (NHANES) showed that consuming 74 grams or more of fructose per day — equivalent to about 2.5 12-ounce cans of sugary soda — correlated significantly with blood pressure of at least 135/85 mm Hg; the relation grew stronger as blood pressure rose. The survey participants had no history of hypertension.

Fructose consumption, in the form of added sugar, has been rising in Western nations since the 1900s, and parallels the growing prevalence of hypertension, said lead investigator Diana I. Jalal, MD, assistant professor of renal medicine at the University of Colorado Health Sciences Center in Aurora.

To examine the relation between the 2, she and her colleagues used the NHANES data to evaluate median fructose intake from food high in added sugar, including bakery products, dairy desserts, chocolate and other candy, dried fruits, honeys, jams, jellies, syrups, and sugar-sweetened soft drinks. Soft drinks alone account for 33% to 40% of fructose consumption in the United States, Dr. Jalal noted.

Fresh fruits were excluded from the analysis because they contain ascorbate, antioxidants, and potassium, which counteract the effect of fructose, Dr. Jalal said during her presentation. Using responses on self-administered dietary questionnaires, the investigators calculated median fructose intake of the participants to be 74 g/day. They then studied the relation between fructose consumption and blood pressure, adjusting for demographics, physical activity, other dietary factors, ascorbate, antioxidants, and potassium, , and findings on laboratory tests. Data from 4528 adults were included in the analysis.

Daily fructose consumption of 74 g or more was independently associated with a 28% increased risk for blood pressure of 135/85 mm Hg or higher, a 36% increased risk for blood pressure of140/90 mm Hg or higher, and an 87% increased risk for blood pressure of 160/100 mm Hg or higher.

The relation was seen only between systolic blood pressure and fructose intake, Dr. Jalal said. There was no correlation between fructose consumption and diastolic blood pressure.

“In subjects with no history of hypertension, there is an independent and significant graded association between high fructose intake and systolic blood pressure levels,” she concluded. The mechanism underlying the relation is unclear.

Among other variables, black ethnicity and waist circumference were significantly associated with higher levels of fructose intake, independent of calorie or carbohydrate consumption. Inverse correlations were seen for sodium and alcohol consumption and fructose. “It seems that people either like their alcohol or they like their sugar, and they like their salt or they like their sugar,” Dr. Jalal told Medscape Nephrology.

This study shows that “we must pay more attention to the nutritional needs of our patients,” said Talal Ikizler, MD, associate professor of medicine at Vanderbilt University, and medical director of the Vanderbilt University Outpatient Dialysis Unit in Nashville, Tennessee.

Nephrologists rarely catch patients at the early stages of renal disease, when risk factor modification might still be possible, explained Dr. Ikizler, who was not involved in this research. However, internists and other primary care physicians do have these opportunities. Whenever possible, patients should be “warned of the consequences of their dietary choices early on.”

Dr. Jalal and Dr. Ikizler have disclosed no relevant financial relationships.

Renal Week 2009: American Society of Nephrology (ASN) 2009 Annual Meeting: Abstract TH-FC037. Presented October 29, 2009.

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