All Posts Tagged With: "autoimmune disease"

It is time to rename LYME;  if we call it LIMES it will change the paradigm and help many more people on the road to recovery than if IV antibiotics suddenly were free for everyone, as often as they wanted them. That is not the best answer for most patients today.  Oxidative treatment would make more sense (UVB/OZONE).

Lyme is all around us but I believe we will help many more if we give up on blaming everything on the tick related introduction of more pathogens than we had the day before we are bit.  Continued

Keep a smile on your face, love in your heart and walk with the angels, holding hands in the “Chain of Love”

PAY IT FORWARD

Linda Heming
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The Dalai Lama said: “Forgiveness doesn’t mean forget what happened.”

LINDA’S COMMENT :  A MUST READ…

Dr. Gordon’s Comments:

A contributor to food allergies/sensitivities has emerged, tick bites. This is a great piece of detective work and seems to not affect B or AB blood groups, as much as Type A or O.

“Scott Commins, an assistant professor of medicine and lead author of the U-Va. Study published in the Journal of Allergy and Clinical Immunology, said that in susceptible people such as Newell, a tick bite that causes a significant skin reaction seems to trigger the production of an antibody that binds to a sugar present on meat called alpha-galactosidase, also known as alpha-gal. When a person who has the antibody eats meat, it triggers the release of histamine, which causes the allergic symptoms: hives, itching and, in the worst case,alpha-galactosidase.”

Of course today with our epidemic of autoimmune disease and leaky gut and low level infections like Chlamydia and CMV in almost everyone, these elevated antibodies to something or even auto-antibodies are very common and may be more dangerous than widely appreciated.

I still encourage those of you who are sensitive to so many foods to understand that leaky gut is epidemic today. I am convinced GMO foods are a contributor, as they introduce Bacillus Theringensis into our bodies, which are now detectible in the blood stream of patients! Bt then causes Dysbiosis.

I hope many of you will try my concept of using my Detox Drink (BioEn’R-G’y C, H Minus, ZeoGold) with my Power Drink and acidophilus to have a healthy gut and be better able to handle the toxic mess our Standard American Diet has become. Remember high levels or the wrong fats from corn and soy etc. set the stage for chronic inflammation. I believe that if this patient wanted to one day eat beef or fish without his allergic reaction without any doubt my F.I.G.H.T.E.M with M.I.C.E. program would get him healthy again and he would not have to suffer these life threatening allergic reactions.

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Link: http://www.washingtonpost.com/wp-dyn/content/article/2009/10/19/AR2009101902874.html

Excerpt:

MEDICAL MYSTERIES
Man’s Sudden Food Allergy Was a Medical Mystery for Months
By Sandra G. Boodman Special to The Washington Post
Tuesday, October 20, 2009

This cannot be happening again, Hayden Newell thought as the angry, red, ferociously itchy welts encircled his waist and spread up his arms. The 57-year-old metallurgist from tiny Boones Mill, Va., who was attending a business lunch in Florida, knew what would probably happen next: His lips would grow numb, making it hard to speak, he would become short of breath and his blood pressure would plummet: all unmistakable signs of anaphylaxis, a potentially fatal allergic reaction. Newell knew from experience that he had to get to an emergency room — fast.

Linda’s comments:  Probiotics and digestive enzymes are a MUST in life today as we know it, but more importantly probiotics and digestive enzymes are vital to recovery of autoimmune disease, lyme disease, Cancer, etc., etc. etc.    What most don’t understand is the best time to begin probiotics and digestive enzymes is BEFOR you get sick….

Dr. Gordon’s comments:

Probiotics are beginning to get the attention they deserve. 

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Link: http://www.nutraingredients.com/Health-condition-categories/Cognitive-and-mental-function/Could-probiotics-affect-behaviour/?utm_source=Newsletter_Product&utm_medium=email&utm_campaign=Newsletter%2BProduct

Excerpt:

Could probiotics affect behaviour?

By Stephen Daniells, 23-Jun-2009

Increasing knowledge of how the gut and brain is opening up the possibilities for probiotics. At the 5th International Yakult Symposium in Amsterdam, Stephen Daniells met Professor John Bienenstock from McMaster University to find out where the current thinking is with probiotics and brain health. 

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21217173&retmode=ref&cmd=prlinks

Excerpt:

Antibiotic-refractory Lyme arthritis may result from Borrelia
burgdorferi-induced autoimmunity in affected joints. Such patients usually
have certain HLA-DRB1 molecules that bind an epitope of B. burgdorferi
outer-surface protein A (OspA), and cellular and humoral immune responses to
OspA are greater in patients with antibiotic-refractory arthritis than in
those with antibiotic-responsive arthritis. Recent work in a mouse model
suggests that, during B. burgdorferi infection, OspA in genetically
susceptible individuals stimulates a particularly strong T(H)1 response,
which may be one of several factors that can help set the stage for a
putative autoimmune response in affected joints. However, vaccination with
OspA did not induce arthritis in this mouse model, and case and control
comparisons in human vaccine trials did not show an increased frequency of
arthritis among OspA-vaccinated individuals.
Thus, a vaccine-induced immune response to OspA does not replicate the
sequence of events needed in the natural infection to induce
antibiotic-refractory Lyme arthritis.

Link: http://www.vetscite.org/publish/items/006234/index.html

Excerpt:

An 11-year study of a population of wild sheep located on a
remote island off the coast of Scotland that gauged the animals’
susceptibility to infection may give new insight into why some
people get sicker than others when exposed to the same illness.
The answer to this medical puzzle may lie in deep-rooted
differences in how animals survive and reproduce in the wild,
according to the study, which was led by Princeton ecologist
Andrea Graham and published in the Oct. 29 issue of Science. The
research revealed that the sheep population over time has
maintained a balance of those with weaker and stronger levels of
immunity and fertility. “This is a groundbreaking study that to
my mind will change our whole understanding of the
immunoheterogenity in animal populations,” said Peter Hudson, the
Willaman Professor of Biology and director of life sciences at
Penn State University. “Graham and colleagues show beautifully
the tradeoffs in the immune system as a balance… that maximizes
reproductive output.”

Gut bacteria may cause autoimmune disease. We have all known this for some time but here is more research getting into how it happens.

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Link: http://www.the-scientist.com/article/display/57782/ 

Excerpt:

The finding 
The trillions of microbes that reside in the human gut shape their host’s immune system—for better or for worse. In a mouse model of autoimmune arthritis, Diane Mathis from Harvard University and colleagues found that gut bacteria can provoke autoimmune disease in distant parts of the body—the joints.

The surprise 
When investigators raised transgenic mice (which develop the disease at 4 weeks of age) in germ-free conditions, the animals developed a milder version of the disease much later. Germ-free mice lack immune cells called T helper 17 cells (Th17), because these cells require the gut bacteria called segmented filamentous bacteria (SFB) to properly develop. When Mathis blocked IL-17—secreted by Th17 cells—in the normally raised mouse model, disease progression was also attenuated.

The link 
Mathis and colleagues showed that after SFB induced the accumulation of Th17 cells in the gut, the immune cells traveled to the spleen, where they helped activate antibody-producing B cells. Since the B cells in this mouse model produced self-attacking antibodies that initiated arthritis, the presence of IL-17 acted like a catalyst, quickening the disease. Though more work remains, “it is not hard to imagine the clinical relevance,” write Rochelle Marie Hinman and Faculty Member John Cambier.

Full article: http://www.foodconsumer.org/newsite/Nutrition/Vitamins/vitamin_d_deficiency_is_why_you_get_flu_0703100554.html

Excerpt:

A new study led by researchers at the University of Copenhagen has confirmed that vitamin D plays an important role in activating immune defenses against infectious diseases like flu.

Vitamin D deficiency has already been linked to a wide spectrum of diseases including heart disease, cancer, diabetes, depression, autoimmune disease and many others.

The study published in the latest edition of Nature Immunology discovers that activation of T-cells to fight infections needs definite help from vitamin D.

Carsten Geisler and colleagues, study authors, explained the role vitamin D plays in the immune responses as follows.

First when the naive T cell recognizes foreign invaders like bacteria or viruses with T cell receptor (TCR), it sends activating signals (1) to the vitamin D receptor gene. The VDR gene then starts producing DVR protein, which binds vitamin D in the T cell (3) and becomes activated. Then the vitamin D bound and activated DVR gets into the cell nucleus and activates the gene for PLC-gamma1 (5), which in turn produces PLC-gamma1 protein (6) and “the T cells can get started”.

More proof that autoimmune disease patients have chronic infections that are not widely recognized; this time we are talking about TB!

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Full article: http://erj.ersjournals.com/cgi/content/abstract/33/3/586

Excerpt:

Screening for active tuberculosis (TB) and latent TB infection (LTBI) is mandatory prior to the initiation of tumour necrosis factor-  inhibitor therapy. However, no agreement exists on the best strategy for detecting LTBI in this population. The aim of the present study was to analyse the performance of the tuberculin skin test (TST) and QuantiFERON®-TB Gold in-tube (QFT-GIT) on LTBI detection in subjects with immunomediated inflammatory diseases (IMID).

The TST and QFT-GIT were prospectively performed in 398 consecutive IMID subjects, 310 (78%) on immunosuppressive therapy and only 16 (4%) had been bacillus Calmette–Guérin (BCG) vaccinated.

Indeterminate results to QFT-GIT were found in five (1.2%) subjects. Overall, 74 (19%) out of 393 subjects were TST-positive and 52 (13%) were QFT-GIT-positive. Concordance between TST and QFT-GIT results was good (87.7%): 13 were QFT-GIT-positive/TST-negative and 35 QFT-GIT-negative/TST-positive. By multivariate analysis both tests were significantly associated with older age. Only the TST was associated with BCG vaccination and radiological lesions of past TB. Use of immunosuppressive drugs differently modulated QFT-GIT or TST scoring.

Other considerations in autism are mitochondrial and nuclear defects.

“Of the 282 individuals with ASD, 14 (10 males and 4 females) met the modified Walker diagnostic criteria for mitochondrial disease. These individuals tested negative on chromosome microarray analysis, fragile X syndrome, Angelman syndrome, and Rett syndrome, among other tests. Neurological characteristics accompanying their ASD included ataxia, dystonia, seizure disorder, and developmental delay. All 14 demonstrated molecular or biochemical problems.”

And don’t forget that the latest information on Autism will be presented at tomorrow’s conference, which will be of special importance for chiropractors. Continued