All Posts Tagged With: "DNA methylation"

A Tale of Two Mice – Epigenetic Research

The epigenetic research is explained very well in the attached text from a video clip that I have put on the www.gordonresearch.com website. The pictures bring this to life and will be very educational to any audience but the conclusion from the video clip is below.

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Full article: http://www.fliqz.com/aspx/permalink.aspxvid=75c53ffb47df42fb85809973823b249d

Excerpt:

Nova
A Tale of Two Mice
In this audio slide show, Dr. Dana Dolinoy of Duke University explains the role that the epigenome, a sort of second genome, plays in regulating the expression of our genes. As Dolinoy notes, we can no longer say with certainty whether genetics or the environment have a greater impact on our health, because the two are inextricably linked through the epigenome. Continued

A Tale of two Mice

The epigenetic research is explained very well in the attached text from a video clip that I have put on the www.gordonresearch.com website. The pictures bring this to life and will be very educational to any audience but the conclusion from the video clip is below.

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Full article:  http://www.fliqz.com/aspx/permalink.aspx?vid=75c53ffb47df42fb85809973823b249d

Excerpt:

Nova
A Tale of Two Mice
In this audio slide show, Dr. Dana Dolinoy of Duke University explains the role that the epigenome, a sort of second genome, plays in regulating the expression of our genes. As Dolinoy notes, we can no longer say with certainty whether genetics or the environment have a greater impact on our health, because the two are inextricably linked through the epigenome.

Posted: July 1, 2008
CHAPTER 1: THE AGOUTI SISTERS

DANA DOLINOY: Hi, I’m Dr. Dana Dolinoy, a post-doctoral research fellow in the laboratory of Randy Jirtle at Duke University. In our laboratory we study epigenetic gene regulation, or how environmental exposures interact with the epigenome to affect long-term health and disease.

So today I’d like to introduce you to two Agouti mice. And as you can see, the yellow mouse is quite obese, and she is also prone to diabetes and cancer. But on the other hand, the brown mouse remains slender and lean and also has a lower risk of developing disease.
But what’s really amazing about these two mice are that they are genetically identical — they are two identical twin sisters from the same mother. So what makes them look so different?