All Posts Tagged With: "IgG."

Cerebrospinal fluid in adults with Lyme

Excerpt:

In acute LNB, all
patients had elevated cerebrospinal fluid (CSF) leukocyte counts. In
contrast to infections by other bacteria, CSF lactate was lower than 3.5
mmol/l in all but 5 patients. The CSF findings did not differ between
polyradiculoneuritis, facial palsy, and meningitis. The CSF in LNB
patients strongly differed from CSF in VM patients with respect to
protein concentration and the CSF/serum albumin quotient.

Lyme pericarditis leading to tamponade

We report the case of a 62-yr-old man who presented with Lyme pericarditis leading to cardiac tamponade shortly followed by an arthritis. IgM and IgG antibodies to Borrelia burgdorferi were demonstrated in serum by indirect immunofluorescence. Borrelia burgdorferi was demonstrated and identified in pericardial fluid by indirect immunofluorescence using serum from a patient with proven Lyme disease and by a monoclonal antibody immuno-gold silver stain. Spirochetes were also found in synovial biopsies using a silver stain. The tamponade was treated with pericardiocentesis; the arthritis was treated with intravenous ceftriaxone (2 g once daily) for 14 days. The patient recovered completely within days of commencing treatment. This case report demonstrates that borrelial infection may lead to pericarditis and cardiac tamponade. Continued

Spirochetes in cardiac biopsies

Linda’s comment:  This report was posted in 1989 but it still is true today.  Many of us Lymies have/had Lyme Carditis.  It can be frightening to say the least.  I was never one to do antibiotics, but I did plenty of anti microbial’s, herbals, supplements and later the FIGHT lifelong daily detox and don’t have those problems today.  Reducing heavy metals and reducing my total body burden of pathogens and toxins has been God sent to me.  You don’t have to use the brands that I chose, but I know the products I used worked, and are still working for me.   I have battled (5) Cancers, (2) Lyme infections, COPD, Arthritis, CHF, Varestrongylus Klapowi worm, and several other health woes, however once I woke up and made the right lifestyle changes, the battles I fought became much easier.  Giving up GMO foods, removing all the toxins,chemicals, pesticides, herbicides, and toxic cleaning supplies from my home made this healing and detox journey much easier. Being a southern cook, it wasn’t as hard as I anticipated to make cooking changes.  My recipes have become just as delicious.  Did I complain when making these changes, you betcha I did.  However, when I begin my research on all the no no’s in my life and finding out the Cancers were environmental Cancers, threw me right into the mission of making changes.  Once I stopped complaining to my self it was much easier.  It became a challenge to prove to myself I could make these changes.  In the beginning I never told my family that they were eating gluten free or Buffalo meat.  When they began to tell me that they knew something was different, but it tasted good to them, I finally admitted about the gluten free and Buffalo. Regards, Linda

Cardiac involvement occurring early in Borrelia burgdorferi infection is a clinical manifestation of human Lyme disease. Therefore, two patients with acute complete atrioventricular heart blocks and unexplained recurrent dizziness were studied. Both patients had significantly elevated serum titers of IgM and IgG antibodies to B. burgdorferi. Right ventricular subendocardial biopsies showed dense infiltrates consisting of lymphocytes and plasma cells. Silver staining revealed spirochetes characteristic of B. burgdorferi near and in the infiltrates, between the muscle fibers, and in the endocardium. One patient responded to penicillin; the other did not, necessitating installation of a pacemaker. Thus, permanent heart damage may result from cardiac involvement in Lyme disease. Continued

Lyme Encephalopathy

Encephalopathy is like fine art: Most people know it when they see it, but there is very little agreement on how to define it. At the 14th International Lyme Disease Conference, Brian A. Fallon, MD,[1] of Columbia University and the New York State Psychiatric Institute, New York, NY, tried to do just that. More importantly, he described the different ways one can define encephalopathy, the strengths and limitations of each approach, and significantly, what other aspects of life can give the impression of encephalopathy where none exists. First, one must evaluate patients with persistent Lyme encephalopathy by asking the following questions:

Is the diagnosis correct?
Are there comorbid psychiatric disorders that could be treated better? Does the patient have a psychogenic medical illness? What was the patient’s response to prior antibiotics?
Was previous treatment adequate? How long was the course, and what was the route of administration? Was there a subsequent relapse Continued

Lyme Encepalopathy

Encephalopathy is like fine art: Most people know it when they see it, but there is very little agreement on how to define it. At the 14th International Lyme Disease Conference, Brian A. Fallon, MD,[1] of Columbia University and the New York State Psychiatric Institute, New York, NY, tried to do just that. More importantly, he described the different ways one can define encephalopathy, the strengths and limitations of each approach, and significantly, what other aspects of life can give the impression of encephalopathy where none exists.
First, one must evaluate patients with persistent Lyme encephalopathy by asking the following questions:

Is the diagnosis correct?
Are there comorbid psychiatric disorders that could be treated better? Does the patient have a psychogenic medical illness? What was the patient’s response to prior antibiotics?
Was previous treatment adequate? How long was the course, and what was the route of administration? Was there a subsequent relapse Continued