immune response – F.I.G.H.T for your health!

Reduced immune response to Lyme

Linda — Wed, 23 Nov 2011 06:21:38 +0000

Linda’s comment: We previously observed that γδ T cells in vitro are activated by Borrelia burgdorferi in a TLR2-dependent manner. We now observe that the activated γδ T cells can in turn stimulate dendritic cells in vitro to produce cytokines and chemokines that are important for the adaptive immune response.

This paralleled greater Borreli a burden in
γδ-deficient mice as well as more cardiac inflammation. These findings
are consistent with a model of γδ T cells functioning to promote the
adaptive immune response during infection.

Lyme bacteria hides out in lymph nodes

Linda — Fri, 17 Jun 2011 06:16:51 +0000

Linda’s comments: What amazes me is they have said for years that those who suffered from MONO ended up having Lyme disease. So now they feel they have made a discovery that many doctors and patients have known about in the alternative arena….Bottom-line, at least they are now publishing about these issues…

Link: http://www.healthtalkandyou.com/uc-davis-finds-lyme-disease-bacteria-in-lymph-nodes/

Excerpt:

UC Davis Finds Lyme Disease Bacteria in Lymph Nodes
by Maejoy Tutor in Diseases on Jun 15, 2011

One of the most significant and considered as threatening and rising diseases in US is the Lyme disease. The bacteria which causes this seems to be hiding particularly in lymph nodes. University of California Davis researchers have reported that this can trigger a considerable immune response, except that it is not too strong to defeat the infection.

Humoral Immune Response in Dogs with Borrelia

Linda — Wed, 14 Jul 2010 05:57:33 +0000

Excerpt:

Lyme arthritis in dogs can be induced under experimental and
natural conditions.
However, the veterinary relevance of canine borreliosis is still
under extensive investigation. The prevalence of symptoms is
clearly low although the risk of tick exposure is high. Current
research focuses on case definitions, methods for diagnosing
clinical disease in dogs, and discrimination between an immune
response to a natural infection versus vaccination.
In this experimental study,
23 dogs raised under tick-free conditions were allocated to two
groups: 11 dogs were vaccinated with a commercial borrelia
vaccine and subsequently developed detectable antibody titers; 12
were walked in a tick-endemic area on two consecutive days. On
day five after exposure engorged ticks were removed from the 12
dogs and analyzed for Borrelia DNA in real-time PCR assay. Blood
samples were taken before exposure/vaccination and at defined
time points thereafter.