By Linda on Jan 14, 2011 in Infections | comments(0)
Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21186776&retmode=ref&cmd=prlinks
Excerpt:
Lyme disease (borreliosis) is an infectious disease caused by the Borrelia
spirochaetes, usually transmitted to humans by the Ixodes ticks. It is
manifested by a wide spectrum of clinical symptoms varying according to the
time elapsed from the infection. The paper describes orofacial symptoms of
the disease in a woman who has suffered from a chronic borreliosis for 3
years.
Multiorgan clinical manifestations of borreliosis might occur in the
masticatory organ and this fact should be taken into consideration in the
differential diagnosis of pain by medical and dental practitioners.
By Linda on Dec 22, 2010 in F.I.G.H.T. | comments(0)
Martin Pall has made a major contribution to our understanding of many of the CHRONIC degenerative diseases we see today. I like the fact that this provides a molecular based explanation that leads to improved understanding of the need for a total nutritional support program in these diseases, which our colleagues all too often dismiss as psychosomatic.
This link will take you into well written materials by Dr Pall that may add to your ability to move beyond today’s differential diagnosis into a more comprehensive understanding of what is really going wrong when our patients develop fibromyalgia, chronic fatigue, chemical sensitivities, etc.
Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com
Link: http://www.thetenthparadigm.org/
Excerpt:
Novel Disease Paradigm Produces Explanations for a Whole Group of Illnesses
A Common Causal (Etiologic) Mechanism for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, Multiple Chemical Sensitivity, Fibromyalgia and Post-Traumatic Stress Disorder
Martin L. Pall, Professor Emeritus of Biochemistry and Basic Medical Sciences,
Washington State University and Research Director, The Tenth Paradigm Research Group.
The Tenth Paradigm of Human Disease
The basic proposal that is developed here and is amplified further in my book and in my other web pages, is that the NO/ONOO- cycle explanatory model is the tenth major paradigm of human disease. There are nine well-accepted paradigms listed below along with the NO/ONOO- cycle:
Major Disease Paradigms
1. Infectious diseases.
2. Genetic diseases.
3. Nutritional deficiency diseases.
4. Hormone dysfunction diseases.
5. Allergies.
6. Autoimmune diseases.
7. Somatic mutation/selection (cancer).
8. Ischemic cardiovascular diseases.
9. Amyloid (including prion) diseases.
10. NO/ONOO- cycle diseases
By Linda on Jul 14, 2010 in Infections | comments(0)
Excerpt:
Lyme arthritis in dogs can be induced under experimental and
natural conditions.
However, the veterinary relevance of canine borreliosis is still
under extensive investigation. The prevalence of symptoms is
clearly low although the risk of tick exposure is high. Current
research focuses on case definitions, methods for diagnosing
clinical disease in dogs, and discrimination between an immune
response to a natural infection versus vaccination.
In this experimental study,
23 dogs raised under tick-free conditions were allocated to two
groups: 11 dogs were vaccinated with a commercial borrelia
vaccine and subsequently developed detectable antibody titers; 12
were walked in a tick-endemic area on two consecutive days. On
day five after exposure engorged ticks were removed from the 12
dogs and analyzed for Borrelia DNA in real-time PCR assay. Blood
samples were taken before exposure/vaccination and at defined
time points thereafter.
By Linda on Jul 13, 2010 in Infections | comments(0)
Excerpt:
June 17, 2010 — Concern that a new human gamma-retrovirus may be transmissible through blood has led one infectious diseases specialist to recommend new steps to protect the US blood supply against possible infection with the virus.
The transfusion medicine organization AABB has formed a task force to study the transmission potential of xenotropic murine leukemia virus–related virus (XMRV), which has been linked to familial prostate cancer and, more recently, to chronic fatigue syndrome (CFS).
By Linda on Apr 28, 2010 in Infections | comments(0)
Full article: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20369726&retmode=ref&cmd=prlinks
Excerpt:
Lyme disease is a multisystem infectious disease with a wide
variety of symptoms involving the skin as well as the nervous
system. Lyme disease is caused by spirochaete Borrelia
burgdorferi transmitted by Ixodes ticks in endemic regions.
A case of 45 year old woman suffering from borreliosis, psoriasis
and depression is presented in the paper. In the study a
standardized screening list was applied to evaluate the
psychiatric health state–Classification of Psychic Disorders
(DSM-IV) and Hamilton Scale. Patient was diagnosed with a major
depressive episode (MDE) according to DSM-IV Diagnosis Criteria.
Patient obtained a score 21 on the 24-item in Hamilton Rating
Scale of Depression.
By Linda on Apr 10, 2010 in Infections | comments(0)
Bartonellosis: an emerging infectious disease of
zoonotic importance to animals,and human beings.
J Vet Emerg Crit Care (San Antonio). 2010 Feb 1;20(1):8-30.
Bartonellosis: an emerging infectious disease of zoonotic
importance to animals and human beings.
Breitschwerdt EB, Maggi RG, Chomel BB, Lappin MR.
Department of Clinical Sciences, Center for Comparative Medicine
and Translational Research, College of Veterinary Medicine, North
Carolina State University, Raleigh, NC 27606.
Objective- To provide a review of clinically relevant
observations related to Bartonella species as emerging pathogens
in veterinary and human medicine. Data
Sources- Literature as cited in PubMed and as generated by each
of the authors who have contributed to various aspects of the
clinical understanding of bartonellosis. Human Data Synthesis-
Important historical and recent publications illustrating the
evolving role of animal reservoirs as a source of human
infection. Veterinary Data Synthesis- Comprehensive review of the
veterinary literature.
Conclusions- In addition to inducing life-threatening illnesses,
such as endocarditis, myocarditis, and meningoencephalitis and
contributing to chronic debilitating disease, such as arthritis,
osteomyelitis, and granulomatous inflammation in cats, dogs, and
potentially other animal species; pets and wildlife species can
serve as persistently infected reservoir hosts for the
transmission of Bartonella spp. infection to veterinary
professionals and others with direct animal contact.
http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pu
bmed&id=20230432&retmode=ref&cmd=prlinks
PMID: 20230432 [PubMed – in process]
By Linda on Mar 1, 2010 in Infections | comments(0)
Excerpt:
Borrelia burgdorferi sensu lato is the causative agent
of Lyme borreliosis in humans. This inflammatory disease can
affect the skin, the peripheral and central nervous system, the
musculoskeletal and cardiovascular system and rarely the eyes.
Early stages are directly associated with viable bacteria at the
site of inflammation. The pathogen-host interaction is complex
and has been elucidated only in part. B. burgdorferi is highly
susceptible to antibiotic treatment and the majority of patients
profit from this treatment
By Linda on Dec 22, 2009 in Infections | comments(0)
The use of new, highly sensitive diagnostic methods has revealed persistent
infections to be a common feature of different tick-borne diseases, such as
babesiosis, anaplasmosis and heartwater. Antigenic variation can contribute to
disease persistence through the continual elaboration of new surface structures,
and we know in several instances how this is achieved. Continued
By Linda on Dec 22, 2009 in Infections | comments(0)
Center for Comparative Medicine, Schools of Medicine and Veterinary Medicine,
University of California at Davis, One Shields Avenue, Davis, California 95616;
Division of Infectious Diseases, Department of Medicine, State University of New
York at Stony Brook, Stony Brook, New York 11794. Continued
By Linda on Dec 16, 2009 in Infections | comments(0)
Traditional Chinese medicine commands a unique position among all traditional medicines because of its 5000 years of history. Our own interest in natural products from traditional Chinese medicine was triggered in the 1990s, by artemisinin‐type sesquiterpene lactones from Artemisia annua L. As demonstrated in recent years, this class of compounds has activity against malaria, cancer cells, and schistosomiasis. Interestingly, the bioactivity of artemisinin and its semisynthetic derivative artesunate is even broader and includes the inhibition of certain viruses, such as human cytomegalovirus and other members of the Herpesviridae family (e.g., herpes simplex virus type 1 and Epstein‐Barr virus), hepatitis B virus, hepatitis C virus, and bovine viral diarrhea virus. Analysis of the complete profile of the pharmacological activities and molecular modes of action of artemisinin and artesunate and their performance in clinical trials will further elucidate the full antimicrobial potential of these versatile pharmacological tools from nature. Continued