By Linda on May 12, 2010 in Infections | comments(0)
Article:
A 36year old male patient presented to emergency cardiology
department because of fatigability. ECG revealed high grade II
atrio-ventricular block and bradycardia of 31beats/min. An
erythema increasing in size to up to 7-8cm in diameter appeared a
month earlier and spontaneously resolved within 10days.
ELISA testing for antibodies against Borrelia burgdorferi IgM was
positive and IgG titer was 1:40. Intravenous ceftriaxone 2g qod,
and 0.5g metronidazole tid lead to regression of grade II block
to grade I block within 2days. Grade I block persisted for an
additional 10days. This is a relatively rare case of early
occurrence of Lyme carditis within one month of exposure as the
first sign of Lyme disease dissemination. Copyright (c) 2010.
Published by Elsevier Ireland Ltd.
Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20226549&retmode=ref&cmd=prlinks
By Linda on Dec 4, 2009 in Infections | comments(0)
We report the case of a 62-yr-old man who presented with Lyme pericarditis leading to cardiac tamponade shortly followed by an arthritis. IgM and IgG antibodies to Borrelia burgdorferi were demonstrated in serum by indirect immunofluorescence. Borrelia burgdorferi was demonstrated and identified in pericardial fluid by indirect immunofluorescence using serum from a patient with proven Lyme disease and by a monoclonal antibody immuno-gold silver stain. Spirochetes were also found in synovial biopsies using a silver stain. The tamponade was treated with pericardiocentesis; the arthritis was treated with intravenous ceftriaxone (2 g once daily) for 14 days. The patient recovered completely within days of commencing treatment. This case report demonstrates that borrelial infection may lead to pericarditis and cardiac tamponade. Continued
