Lyme neuroborreliosis (LNB) – F.I.G.H.T for your health! http://lymebook.com/fight Linda Heming describes her Lyme disease healing journey Wed, 06 Nov 2013 05:54:37 +0000 en-US hourly 1 https://wordpress.org/?v=4.9.25 Axonal Damage from Lyme http://lymebook.com/fight/axonal-damage-from-lyme/ http://lymebook.com/fight/axonal-damage-from-lyme/#respond Wed, 23 Nov 2011 06:22:37 +0000 http://lymebook.com/fight/?p=2801 Linda’s  comment:  Lyme neuroborreliosis (LNB) is the most frequent tick-borne infectious disease of the central nervous system. In acute LNB and the rare **chronic state of infection**, patients can experience cognitive deficits such as attention and memory disturbances.

Continuous exposure to intrathecal B. burgdorferi OspC
led to activation of microglia and axonal damage without demonstrable
cognitive impairment in experimental mice. These results suggest that
long-term intrathecal exposure to OspC resulted in axonal damage that
may underlie the neurologic manifestations in chronic LNB.

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