Excerpt:

Lyme optic neuritis (ON) is a rare disease and only a few cases
have been reported. We describe two cases of isolated Lyme ON,
one with recurrence 9 months after the appearance of initial
symptoms. Diagnosis criteria for multiple sclerosis and
neuromyelitis optica were not met. The etiological diagnosis was
based on European case definition criteria for neuroborreliosis.
Both patients had positive serum and cerebrospinal fluid
serology, a positive intrathecal anti-Borrelia antibody index,
and a good outcome on ceftriaxone. Specific diagnosis of Lyme ON
is important since improvement of visual acuity is possible with
specific antibiotherapy, even after many months. Copyright (c)
2010 Elsevier B.V. All rights reserved.