Hypothyrodism and endothelial dysfunction – a message from Dr. Gordon
By Linda on Aug 30, 2010 in F.I.G.H.T. | comments(0)
This mainstream report found that one year of Levothyroxine treatment does not fully restore endothelial function. This is important for two reasons:
1. Mainstream is beginning to acknowledge that low thyroid functioning contributes to heart disease.
2. Also I suggest that Heart Disease is multifactorial and, therefore, MONOTHERAPY will often fail.
Many would feel that the type of thyroid replacement is a partial explanation but I feel that we would need to look at Iodine to have provided a better outcome. But all the elements of my FIGHT program are relevant for those seeking OPTIMAL improvement in cardiac or endothelial function. There is always low levels of some nutrients (F), take your pick from Vit D to Magnesium. There will always be the high probability of CMV infection (I). And, probably some Genetic issues with some epigenetic changes increasing the need for methylation support including the active forms of Folic Acid (G). Then there will always be some element of heavy metals (H: Lead, etc.) and there will be Toxins in everyone that include endocrine disruptors and neurotoxins (T)!
Thus this report should help prove the need for broadly based approaches in dealing with chronic illness such as endothelial dysfunction leading to atherosclerosis.
Garry F Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com
Full article: http://www.ingentaconnect.com/content/bsc/cend/2009/00000070/00000006/art00017
Excerpt:
Abstract:
Summary Objective
Hypothyroidism is associated with elevated cardiovascular risk, not fully explained by classical risk factors. Instead, endothelial dysfunction may link hypothyroidism to atherosclerosis. The effect of levothyroxine substitution on endothelial function has been sparsely studied and the results are unclear. This study tested endothelial function as estimated by concomitant measurements of endothelial dependent vascular dilatory capacity and plasma concentration of von Willebrand factor antigen in patients with hypothyroidism and further examined the impact of subsequent levothyroxine substitution.
