Acute neuroborreliosis with CNS involvement
By Linda on Jul 20, 2010 in Infections | comments(0)
Full article: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20561635&retmode=ref&cmd=prlinks
Excerpt:
RESULTS: Eleven patients who presented with acute central nervous
system (CNS) syndrome fulfilled the diagnostic criteria for
neuroborreliosis. In the CSF studies, lymphocytic pleocytosis
with elevation of total protein and normal glucose was noted in 9
patients. The clinical syndromes were confirmed by magnetic
resonance imaging and electrophysiological studies. Ten of 11
patients were found to have brain stem or spinal cord lesions on
neuroimaging studies, and 8 patients had concomitant peripheral
nervous system involvement with electrophysiological evidence of
multiple root lesions with an acute or subacute course.
CONCLUSIONS: Lyme neuroborreliosis presenting as acute CNS
syndrome with peripheral nervous system involvement
simultaneously in the disease course, especially acute
myelopolyradiculitis, in Taiwan is different from Lyme
neuroborreliosis seen in Europe and North America. The treatment
outcome is variable and based on the severity of initial
neurological deficits, early diagnosis, and early management.
Copyright (c) 2010 Elsevier B.V. All rights reserved.
