serum levels of anti-Borrelia antibodies – F.I.G.H.T for your health! http://lymebook.com/fight Linda Heming describes her Lyme disease healing journey Wed, 06 Nov 2013 05:54:37 +0000 en-US hourly 1 https://wordpress.org/?v=4.9.25 Reduced immune response to Lyme http://lymebook.com/fight/reduced-immune-response-to-lyme/ http://lymebook.com/fight/reduced-immune-response-to-lyme/#respond Wed, 23 Nov 2011 06:21:38 +0000 http://lymebook.com/fight/?p=2799 Linda’s comment:  We previously observed that γδ T cells in vitro are activated by Borrelia burgdorferi in a TLR2-dependent manner. We now observe that the activated γδ T cells can in turn stimulate dendritic cells in vitro to produce cytokines and chemokines that are important for the adaptive immune response.

 This paralleled greater Borreli a burden in
γδ-deficient mice as well as more cardiac inflammation. These findings
are consistent with a model of γδ T cells functioning to promote the
adaptive immune response during infection.

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