All Posts Tagged With: "spirochete"

Lyme disease (borreliosis) is a systemic illness resulting from infection
with the spirochete Borrelia burgdorferi. It is transmitted to humans by the
bites of infected ticks belonging to several species of the genus Ixodes.
After the bacteria enter the body via the dermis, most patients develop the
early, localised form of Lyme disease, which is characterised by erythema
migrans and influenza-like symptoms. This disease may also affect the heart,
nervous system and joints. The neurological findings of this disease may
include peripheral and central nervous system signs.
A 21-year-old woman attended a family medicine outpatient clinic complaining
of unexplained pain and muscle power loss in her lower extremities. The
problem had started in her right leg 3 months earlier and worsened in the
last week. She had a neurology consultation and was hospitalised. Her
neurological examination revealed bilateral facial paralysis and sensory
impairment. Immunoglobulin M antibody to B. burgdorferi was positive on
Western blotting in both serum and cerebrospinal fluid. The patient was
diagnosed with subacute neuroborreliosis and treated.

Acta Neurol Belg. 2009 Dec;109(4):326-9.

Koc F, Bozdemir H, Pekoz T, Aksu HS, Ozcan S, Kurdak H.

Department of Neurology, Cukurova University School of Medicine, Adana,
Turkey.
koc.filiz@gmail.com

Full article:

http://www.springerlink.com/content/b8×4742136623114/

Excerpt:

Abstract Dilated cardiomyopathy (DCM) represents the third most common cause of heart failure and the most frequent cause of heart transplantation. Infectious, mostly viral, and autoimmune mechanisms, together with genetic abnormalities, have been reported as three major causes of DCM. We hypothesized that Lyme disease (LD), caused by spirochete Borrelia burgdorferi (Bb), might be an important cause of new-onset unexplained DCM in patients living in a highly endemic area for LD such as the Czech Republic.

Lyme Disease, caused by the spirochete Borrellia burgdorferi, is the most common vector-borne disease in the United States. Clinically, it primarily affects the skin, joints, nervous system, and heart. Lyme carditis occurs in 4%-10% of adults with Lyme disease. Transient variable-level atrioventricular blocks, occurring in 77% of adults with Lyme carditis, are the most common cardiac manifestation. Up to 50% of Lyme carditis patients may develop complete heart block. The incidence of Lyme carditis in the pediatric population is not well established. We present a pediatric patient with a transient asymptomatic complete heart block resulting from Lyme carditis, an under-recognized complication of Lyme disease in the pediatric population. Continued

Lyme Disease is transmitted by an arthropod, the Ixodes dammini tick. The spirochete causing the disease is the Borrelia burgdorferi.

Over the past nine years, we have treated over three hundred children for Lyme Disease in the hospital because they had significant neurologic manifestations of Lyme Disease or, in the minority of cases, an arthritis necessitating hospitalization for intravenous antibiotics. Continued