Bb suppression by Nod2

Linda’s comment:  B. burgdorferi infection of Nod2 deficient mice resulted in increased rather than decreased arthritis and carditis compared to control mice. They are saying a model where Nod2 has an enhancing role in activating inflammation in early infection, but moderates inflammation after prolonged exposure to the organism through induction of tolerance.  I suffered from Lyme Carditis, but thanks to Gemmotherapy they were able to kill the Lyme spirochetes and parasites and clear it up….it is not a fun thing to do through.  What is scary and sad is Cardiologists don’t have a clue when a patient shows up in ER with chest pains…

 

Link: http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017414

Excerpt:

We propose a model where Nod2 has an enhancing role
in activating inflammation in early infection, but moderates
inflammation after prolonged exposure to the organism through induction
of tolerance.