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Dementia and Geriatric Cognitive Disorders

 Dement Geriatr Cogn Disord 2009;28:275-280 (DOI: 10.1159/000242439)

Dementia and Geriatric Cognitive Disorders   10/01/2009
Vol. 28, No. 3, 2009   
 
A Prospective Study on the Development of Alzheimer’s Disease with Regard to Thyroid-Stimulating Hormone and Homocysteine
Sylvia Annerboa, Miia Kivipeltoa, b, Johan Lökka

aDepartment of Neurobiology, Care Sciences and Society, and
bAging Research Center, Karolinska Institutet, Stockholm, Sweden
 Abstract

Background/Aim: The combination of elevated total homocysteine (tHcy) levels and low levels of thyroid-stimulating hormone (TSH) are linked to Alzheimer’s disease (AD) in some studies, although the evidence is mixed. Our objective was to prospectively investigate the association between tHcy and TSH and the subsequent development of AD. Continued