All Posts Tagged With: "5’MTHF"

Folate & Nutritional Status – with Comments by Dr. Gordon

Dr. Gordon’s Comments:

5’MTHF issues are much more complex than is generally recognized, so normal test results can mean nothing. Whatever you knew until today is not enough to protect your patients and loved ones.

The attached NEJM article from July 9 adds considerable likelihood that when someone tells you that the patient’s nutritional status is just fine, they very likely may be dead wrong. The patient suffers seizures and mental disorders that fail to respond to anything because you had not read the attached, which found that the level of folic acid was fine everywhere except in the cerebral spinal fluid. Now they can explain what is going on and it amenable to proper folate treatment, as found in Beyond B-12 sublingual tablets available only from Longevity Plus.

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Link: http://gordonresearch.com/articles_various/NEJMoa043160.pdf

Excerpt:

In infantile-onset cerebral folate deficiency, 5-methyltetrahydrofolate (5MTHF) levels in the cerebrospinal fluid are low, but folate levels in the serum and erythrocytes are normal. We examined serum specimens from 28 children with cerebral folate deficiency, 5 of their mothers, 28 age-matched control subjects, and 41 patients with an unrelated neurologic disorder. Serum from 25 of the 28 patients and 0 of 28 control subjects contained high-affinity blocking autoantibodies against membrane-bound folate receptors that are present on the choroid plexus.

New study says: Autism NOT Genetic

Linda’s Comments: This destroys the “expert” standing of so many autism so-called experts so do not expect overnight acceptance of the environment causation, which to anyone not involved in genetic research will find is clearly the logical explanation for not just autism but the fact that in USA one in four in school today are on drug therapy for some condition, diebetes, asthma, mental issues including depression adhd, obsessive compulsive and so on. 

Dr. Gordon’s Comments:

This is a bombshell! Autism genetic causation with millions of dollars invested in this wrong direction is all but dead when the world reads the attached in-depth report.

Of course, erroneous ideas hang around in medicine for years, as there is so much money involved in sticking with out-moded concepts. This destroys the “expert” standing of so many autism so-called experts so do not expect overnight acceptance of the environment causation, which to anyone not involved in genetic research will find is clearly the logical explanation for not just autism but the fact that in USA one in four in school today are on drug therapy for some condition, diebetes, asthma, mental issues including depression adhd, obsessive compulsive and so on. 

This latest large study moves the pendulum away from genetic causation back to environment!! This study is carefully reported here in all detail so if you are involved in autism please read the attached in its entirety, as there are important details you will want to express accurately if you are advising patients or teaching.

I have always known that what Andrew Wakefield reported on, see his website and book Callous Disregard, had merit (IE MMR triggered autism in what had seemed to be normal children up until then). I have dealt with many of these families and attended numerous conferences

However, things are not always simple A + B = C and Thiomersal may not be acting alone and there are these Epigenetic issues we know are happening when substances like Bisphenol A impair methylation, as Randy Jirtle at Duke has documented in Agouti mice. Then the issue becomes one of what are the contributing environmental toxins and they may well vary from case to case. Then when you try to study which nutrient deficiencies are contributing to the autism spectrum, you have issue including D, Magnesium etc and now issues around the need for methylation support in order to better handle the load of toxins found in every child’s cord blood (see Ten Americans at www.ewg.org). 

Then the bomb shell of cerebral folate deficiency now reported in NEJM last week where we find that some antigen is blocking the folate receptors in brain and the only hint of nutrient deficiency was documented only in cerebral spinal fluid. Now we have many potential culprits for this new autoimmune disease of the folate receptor – milk protein or whatever you want to implicate to help explain why the folate receptor in brain are blocked and cannot take up folic acid unless in the form of Folinic acid or 5’MTHF and apparently needed by some in significant orthomolecular levels.

Now we have the time line of events and a turning point in the disease was 1988, which we now find is when vaccine manufacturers turned away from egg and incorporated aborted fetal tissue for vaccine production. 

WILL someone ever make sense of all this so that we can stop this epidemic? 

I vote for anyone wanting a healthy baby to start a one or two year aggressive detox program for prospective mom and dad along the lines I advocate with oral chelation including my Power Drink with ZeoGold added along with regular exercise and some sauna exposure to enhance sweating, as a minimum.

Then hopefully start a boycott of all vaccines made on aborted fetal tissue that includes 24 of them today. That would be nice but since that in some countries is met with jail terms and a gun pointed at the prospective recipient of the vaccine, maybe we have to settle for now with trying to decrease the number of adverse outcomes by at minimum using aggressive Vitamin C based oral program. That means using a minimum of one gram per 10# of weight or roughly for year of age, as one program to try to diminish the clear risk I see in associated with current vaccine use in a world population whose immune system is compromised from birth with over 220 known toxins including an average of over 1000 times more lead in tissues than was present 700 years ago (see Cal Tech, Clair Patterson). 

Garry F. Gordon MD,DO,MD(H)
President, Gordon Research Institute
www.gordonresearch.com

Link: http://www.ageofautism.com/2011/07/new-autism-twin-study-demolishes-decades-long-belief-in-genetic-causation.html

Excerpt:

For over two decades now, so-called “autism experts” have been claiming that autism is more than 90% caused by genes. The influence of these claims on autism policy and research funding is hard to overstate. But few realize that the basis of these claims hangs on a fragile evidence base: two small twin studies–one from Great Britain, the other from Scandinavia–that reported high rates of concordance for autism among identical twins and no concordance at all among fraternal twins. Last week, the largest and most rigorous twin study ever conducted, the California Autism Twin Study (CATS) reported contradictory new evidence that struck a devastating blow to these claims. The CATS identical twins had lower and the fraternal twins higher concordance rates than past studies, a striking finding that suggests that instead of being highly heritable, the vast majority of autism cases stem from environmental causes.