Archive for February, 2011

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21156061&retmode=ref&cmd=prlinks

Excerpt:

RESULTS: This study
reveals the digestive machinery of the I. ricinus during the course of
blood-feeding on the host. The dynamic profiling of concentrations,
activities and mRNA expressions of the major digestive enzymes demonstrates
that the de novo synthesis of peptidases triggers the dramatic increase of
the hemoglobinolytic activity along the feeding period. Overall
hemoglobinolysis, as well as the activity of digestive peptidases are
negligible at the early stage of feeding, but increase dramatically towards
the end of the slow feeding period, reaching maxima in fully fed ticks. This
finding contradicts the established opinion that blood digestion is reduced
at the end of engorgement.
Furthermore, we show that the digestive proteolysis is localized
intracellularly throughout the whole duration of feeding. 
CONCLUSIONS: Results suggest that the
egressing proteolytic system in the early stage of feeding and digestion is
a potential target for efficient impairment, most likely by blocking its
components via antibodies present in the host blood. Therefore, digestive
enzymes are promising candidates for development of novel ‘anti-tick’
vaccines capable of tick control and even transmission of tick-borne
pathogens.

Link: http://www.liebertonline.com/doi/abs/10.1089/vbz.2009.0215

Excerpt:

 The epidemiology of vector-borne zoonotic diseases is determined by
encounter rates between vectors and hosts. Alterations to the behavior of
reservoir hosts caused by the infectious agent have the potential to
dramatically alter disease transmission and human risk. We examined the
effect of Borrelia burgdorferi, the etiological agent of Lyme disease, on
one of its most important reservoir hosts, the white-footed mouse,
Peromyscus leucopus. We mimic natural infections in mice using the vector
(Black-legged ticks, Ixodes scapularis) and examine the immunological and
behavioral responses of mouse hosts. Despite producing antibodies against B.
burgdorferi, infected mice did not have elevated white blood cells compared
with uninfected mice. In addition, infected and uninfected mice did not
differ in their wheel-running activity. Our results suggest that infection
with the spirochete B. burgdorferi has little impact on the field activity
of white-footed mice. Lyme disease transmission appears to be uncomplicated
by pathogen-altered behavior of this reservoir host.

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21289156&retmode=ref&cmd=prlinks

Excerpt:

In this study we compared some common Bartonella culturing methodologies
using four diverse species causing human illnesses. Based on a review of the
literature, we focused on three major inconsistencies between protocols:
base media, cell co-culture and temperature. Our data showed that B. tamiae
demonstrated temperature-dependent growth limitations between common
culturing conditions only 2 degrees C apart. Additionally, growth of B.
quintana was significantly enhanced by the presence of mammalian cell
co-culture within mammalian culture conditions, however when the media was
modified to incorporate insect culture-based media, co-culturing with
mammalian cells was no longer needed. In this study, we were able to
overcome these temperature and cell dependent limitations and accommodate
all of the strains tested by combining mammalian culture-based media with
insect culture-based media.

It is  no too late to come to Phoenix for these two conferences !  You will come away understanding that when you combine my F.I.G.H.T.  Program with the missing link, healing with Physics, using the modalities you can personally experience at my conference, you will experience amazing healing results!

Sincerely,

G.F. Gordon MD DO MD(H.)

____

To anyone interested in Infinite Wellness;

I have found unique synergy combining the biochemistry, like my FIGHT program with the PHYSICS we can no longer ignore. This approach is changing the lives of very ill patients, often almost overnight.

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You are invited to attend one or more of my 3 workshops being held in Phoenix March 3-7 in conjunction with the great conference offered 3/4/11 by AHIMA. Flyers and registration information are attached. NOTE: Admission is free on 3/6/11 from Noon until 7 PM and only $50 on other dates if you also register for AHIMA conference, $100 if you do not.

Here you will learn that Physics is more important than Biochemistry in determining how you FEEL and how you HEAL! Without a magnetic field there is no life and the experts believe that the earth’s electromagnetic field hasdropped from nearly 30 Gauss at the time of dinosaurs to 0.3 Gauss now. (more)

Register for AHIMA Conference Here

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Link: http://www.cdc.gov/ncidod/eid

Excerpt:

Bacterial Population Genetics in Infectious Disease addresses a set of issues that are extremely provocative in the current climate in which progress is rapidly changing the microbiological landscape. From this perspective, the volume appears at a key moment because of 2 major challenges that have arisen since the beginning of the genomic era: 1) defining what constitutes a species and how to determine this, and 2) determining the structure of the population of the most common bacterial pathogens.

The book opens with a review of the concepts and methods that make it possible to analyze bacterial populations genetically. This presentation immediately brings to the forefront the question of how to define what constitutes a bacterial species (if there is conceptually even such a thing) and the variable evolutionary nature of bacteria. The differences among complexes within species, species, and clones are shown with clear diagrams useful for teaching. In addition, the text also evaluates the lateral transfer of genes, one of the elements that constitute the bacterial genome repertoire, including its effects on the attempts at classification of bacteria. The evolutionary demography of bacterial populations is then examined. These concepts are essential for comprehending and teaching modern microbiology.

In addition, the text describes techniques for evaluating bacterial diversity, such as the search for single-nucleotide polymorphisms or repeats by using sequences encoding proteins or not. These techniques can play a key part in the identification of the clones.

The second part of the book is specifically relevant to clinical microbiology, particularly to emerging bacterial pathogens. The genetic populations of Bacillus anthracis,Campylobacter spp., Enterococcus spp., Borrelia burdorferi, Neisseria meningitidis,Escherichia coli, Salmonella spp., Staphylococcus spp., and Streptococcus spp. are analyzed. The importance of genomic recombinations in microbial evolution is particularly stressed for Streptococcus spp., Neisseria spp., and E. coli, for which the number of recombinations is considered to be higher than that of the number of changes; this conclusion likely alters our perception of the evolution of bacteria. Lastly, a general hypothesis is proposed for Salmonella spp.: that their antigens are selected by passage through specific phagocytic protists from their animal hosts with which they have cospeciation. This assumption is bold and intriguing.

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21279705&retmode=ref&cmd=prlinks

Excerpt:

Human ehrlichiosis is the term for a collection of tick-borne diseases
caused primarily by obligate intracellular bacteria of the Ehrlichia
species.
Ehrlichiosis is characterized by a mild to severe illness, with
approximately 3-5% of cases proving fatal despite receiving appropriate
care. This report presents the case of a 60 year-old woman who was found
collapsed and unresponsive in her home after an indeterminate time; possibly
for up to 48 h.
Despite rigorous resuscitative care and antibiotic treatment, the patient
lapsed into multi-organ failure and died. Subsequent analysis by microscopic
examination, PCR and immunohistochemistry revealed the patient died from an
infection of Ehrlichia chaffeensis. Clinicians and pathologists must be
aware of this emergent disease in order to make a timely and appropriate
diagnosis.
Discussion of the patient’s clinical, laboratory and autopsy findings as
well as treatment of Ehrlichia chaffeensis infections is presented.

Excerpt:

Lyme neuroborreliosis—characterized as chronic, necrosuppurative to nonsuppurative, perivascular to diffuse meningoradiculoneuritis—was diagnosed in 2 horses with progressive neurologic disease. In 1 horse, Borrelia burgdorferi sensu stricto was identified by polymerase chain reaction amplification of B burgdorferi sensu stricto–specific gene targets (ospA, ospC, flaB, dbpA, arp). Highest spirochetal burdens were in tissues with inflammation, including spinal cord, muscle, and joint capsule. Sequence analysis ofospA, ospC, and flaB revealed 99.9% sequence identity to the respective genes in B burgdorferi strain 297, an isolate from a human case of neuroborreliosis. In both horses, spirochetes were visualized in affected tissues with Steiner silver impregnation and by immunohistochemistry, predominantly within the dense collagenous tissue of the dura mater and leptomeninges.

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21144716&retmode=ref&cmd=prlinks

Excrept:

Lyme borreliosis is a zoonosis characterized by great clinical polymorphism.
We report 2 cases in patients who presented ocular manifestations: one
anterior uveitis in an adult, which resolved under treatment, and one
posterior uveitis in a child, whose initial ophthalmologic examination
already showed retinal fibrous scars including the macular area. Lyme
disease is on the long list of causes that must be discussed in cases of
uveitis. The diagnosis is based on a series of epidemiological, clinical,
and biological arguments with Western Blot serological profile analysis.
Treatment is based especially on intravenous antibiotics. Copyright (c) 2010

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21217173&retmode=ref&cmd=prlinks

Excerpt:

Antibiotic-refractory Lyme arthritis may result from Borrelia
burgdorferi-induced autoimmunity in affected joints. Such patients usually
have certain HLA-DRB1 molecules that bind an epitope of B. burgdorferi
outer-surface protein A (OspA), and cellular and humoral immune responses to
OspA are greater in patients with antibiotic-refractory arthritis than in
those with antibiotic-responsive arthritis. Recent work in a mouse model
suggests that, during B. burgdorferi infection, OspA in genetically
susceptible individuals stimulates a particularly strong T(H)1 response,
which may be one of several factors that can help set the stage for a
putative autoimmune response in affected joints. However, vaccination with
OspA did not induce arthritis in this mouse model, and case and control
comparisons in human vaccine trials did not show an increased frequency of
arthritis among OspA-vaccinated individuals.
Thus, a vaccine-induced immune response to OspA does not replicate the
sequence of events needed in the natural infection to induce
antibiotic-refractory Lyme arthritis.

Greetings,

Jeffrey Smith, the world’s leading spokesperson on the health dangers of Genetically Modified Organisms (GMOs) will be at the 6th Annual IIPA Symposium at the Imperial Palace, Las Vegas Nevada on February 27, 2011 at 12:00 PM for a presentation on the ‘ Health Risks of Dangerous Genetically Modified Foods and How to Avoid Them’ with a book signing to follow.  

One day only pass to the IIPA for the lecture, $35.   

For more information on the IIPA Symposium and their full speaker list, plese visit their website below:
http://www.iridologyassn.org

For maps and information on the Imperial Palace, visit:
http://www.imperialpalace.com

Warm Regards,

The Staff at The Institute for Responsible Technology