All Posts Tagged With: "Department of Pathology"

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21217002&retmode=ref&cmd=prlinks

Excerpt:

Department of Pathology, Division of Microbiology and Immunology, University
of Utah Medical School, Salt Lake City, UT 84112; Institute for Genome
Sciences, University of Maryland, School of Medicine, Department of
Microbiology and Immunology, Baltimore, MD 21201; Department of Biological
Sciences, Hunter College of the City University of New York, New York, NY
10065; Biology Department, Brookhaven National Laboratory, Upton, NY 11793;
Department of Medicine, Health Science Center, Stony Brook University, Stony
Brook, NY 11794; Department of Medicine, University of Medicine and
Dentistry of New Jersey-New Jersey Medical School, Newark, NJ 07103.

Human Lyme disease is caused by a number of related Borrelia burgdorferi
sensu lato species. We report here the complete genome sequence of Borrelia
sp.
isolate SV1 from Finland. It is a so far the closest known relative of B.
burgdorferi sensu stricto, but it is sufficiently genetically distinct from
that species that it and its close relatives warrant its candidacy as a new
species status. We suggest that it should be named Borrelia finlandensis

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21187937&retmode=ref&cmd=prlinks

Excerpt:

The obligately intracellular bacterium Ehrlichia chaffeensis that resides in
mononuclear phagocytes is the causative agent of human monocytotropic
ehrlichiosis. Ehrlichia muris and Ixodes ovatus Ehrlichia (IOE) are agents
of mouse models of ehrlichiosis. The mechanism by which Ehrlichia are
transported from an infected host cell to a non-infected cell has not been
demonstrated.

Full article: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20513551&retmode=ref&cmd=prlinks

Excerpt:

Human ehrlichiosis and anaplasmosis are acute febrile tick-borne
diseases caused by various members of the genera Ehrlichia and
Anaplasma (Anaplasmataceae).
Human monocytotropic ehrlichiosis has become one of the most
prevalent life-threatening tick-borne disease in the United
States. Ehrlichiosis and anaplasmosis are becoming more
frequently diagnosed as the cause of human infections, as animal
reservoirs and tick vectors have increased in number and humans
have inhabited areas where reservoir and tick populations are
high.
Ehrlichia chaffeensis, the etiologic agent of human
monocytotropic ehrlichiosis (HME), is an emerging zoonosis that
causes clinical manifestations ranging from a mild febrile
illness to a fulminant disease characterized by multiorgan system
failure. Anaplasma phagocytophilum causes human granulocytotropic
anaplasmosis (HGA), previously known as human granulocytotropic
ehrlichiosis. This article reviews recent advances in the
understanding of ehrlichial diseases related to microbiology,
epidemiology, diagnosis, pathogenesis, immunity, and treatment of
the 2 prevalent tick-borne diseases found in the United States,
HME and HGA.