Infections

Linda’s comment…..ACS200 truly does kill Borrelia Burgdorferi…I’m a walking example….

http://www.resultsrna.com/products/acs_200_proven_to_kill_borrelia_burgdorferi.php

Linda’s comment:::: This man is dangerous…..FOLLOW THE MONEY FOLKS….

The bacterial organism behind a newly identified tick-borne illness found halfway across the world showed up in Durland Fish’s lab in Connecticut a decade ago.

http://www.ctmirror.org/story/13955/lyme-new-tick-borne-disease-yale

Strange????????? Fishboy, should be locked up to protect us….FOLLOW THE MONEY!!

Linda’s comment: Mycoplasma infections in India and most describe clinical disease in individual dogs, diagnosed by morphological observation of the microorganisms in stained blood smears.

ABSTRACT: BACKGROUND: There are few published reports on canine Babesia,
Ehrlichia, Anaplasma, Hepatozoon and haemotropic Mycoplasma infections
in India and most describe clinical disease in individual dogs,
diagnosed by morphological observation of the microorganisms in stained
blood smears. This study investigated the occurrence and distribution of
canine tick-borne disease (TBD) pathogens using a combination of
conventional and molecular diagnostic techniques in four cities in India.

Linda’s  comment:  Lyme neuroborreliosis (LNB) is the most frequent tick-borne infectious disease of the central nervous system. In acute LNB and the rare **chronic state of infection**, patients can experience cognitive deficits such as attention and memory disturbances.

Continuous exposure to intrathecal B. burgdorferi OspC
led to activation of microglia and axonal damage without demonstrable
cognitive impairment in experimental mice. These results suggest that
long-term intrathecal exposure to OspC resulted in axonal damage that
may underlie the neurologic manifestations in chronic LNB.

Linda’s comment:  We previously observed that γδ T cells in vitro are activated by Borrelia burgdorferi in a TLR2-dependent manner. We now observe that the activated γδ T cells can in turn stimulate dendritic cells in vitro to produce cytokines and chemokines that are important for the adaptive immune response.

 This paralleled greater Borreli a burden in
γδ-deficient mice as well as more cardiac inflammation. These findings
are consistent with a model of γδ T cells functioning to promote the
adaptive immune response during infection.

Linda’s comment: Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi.

CONCLUSION: Antibiotics have varying effects on the different
morphological forms of B. burgdorferi. Persistence of viable organisms
in round body forms and biofilm-like colonies may explain treatment
failure and persistent symptoms following antibiotic therapy of Lyme
disease.

Linda’s Comment:   Bell’s palsy and Lyme neuroborreliosis are the two most common diagnoses in patients with peripheral facial palsy in areas endemic for Borrelia burgdorferi.\

Excerpt:

CONCLUSIONS: We found that the time of the year, associated neurological
symptoms and mononuclear pleocytosis were strong predictive factors for
Lyme neuroborreliosis as a cause of peripheral facial palsy in an area
endemic for Borrelia.

Linda’s comment; Historically, flea-borne diseases are among the most important medical diseases of humans. Plague and murine typhus are known for centuries while the last years brought some new flea-transmitted pathogens, like R. felis and Bartonella henselae.

Excerpt:

ABSTRACT: Historically, flea-borne diseases are among the most important
medical diseases of humans. Plague and murine typhus are known for
centuries while the last years brought some new flea-transmitted
pathogens, like R. felis and Bartonella henselae.

http://pediatrics.aappublications.org/content/128/4/e1019.abstract?etoc

Linda’s comment…Evidence is emerging for differential pathogenicity among Borrelia burgdorferi genotypes in the United States. By using two linked genotyping systems, ribosomal RNA intergenic spacer type (RST) and outer surface protein C (OspC), we studied the inflammatory potential of B. burgdorferi genotypes in cells and patients with erythema migrans or Lyme arthritis.

Link: http://www.ncbi.nlm.nih.gov/pubmed/21641395

Excerpt:

Differences among genotypes were not as great in patients
with Lyme arthritis, but those infected with RST1 strains more often had
antibiotic-refractory arthritis. Thus, the B. burgdorferi RST1 (OspC type A)
genotype, followed by the RST3 (OspC type I) genotype, causes greater
inflammation and more severe disease, establishing a link between spirochetal
virulence and host inflammation