By Linda on Oct 22, 2010 in Infections | comments(0)
Full article: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20833105&retmode=ref&cmd=prlinks
Excerpt:
After 2 decades of Bartonella research, knowledge on transmission
and pathology of these bacteria is still limited. Bartonella spp.
have emerged to be important pathogens in human and veterinary
medicine. For humans, B. henselae is considered to represent the
most relevant zoonotic Bartonella species and is responsible for
cat scratch disease, bacillary angiomatosis, and other disorders.
Over the years, many Bartonella species have been isolated from
humans, cats, dogs, and other mammals, and infections range from
an asymptomatic state (e.g., animal-specific species) to even
life-threatening diseases (e.g., Oroya fever). It is obvious that
the analysis of pathogenicity mechanisms underlying Bartonella
infections is needed to increase our understanding of how these
pathogens adapt to their mammalian hosts resulting in acute or
chronic diseases. Copyright (c) 2010. Published by Elsevier GmbH.
By Linda on Sep 17, 2010 in Infections | comments(0)
Full article: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20823366&retmode=ref&cmd=prlinks
Excerpt:
RESULTS: B. henselae and related
bacterial species are transmitted among cats and dogs by
arthropod vectors. In the absence of these vectors, disease does
not spread amongst the animals. On the other hand, disease can be
spread to humans by bite and scratch as well as by arthropod
vectors. Animals commonly infected with B. henselae and arthropod
vectors are discussed.
CONCLUSIONS: Clinicians should be aware that a common illness,
cat scratch disease, can be transmitted by arthropod vectors and
a history of an animal scratch or bite is not necessary for
disease transmission.
By Linda on Jun 29, 2010 in Infections | comments(0)
Full article: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20519614&retmode=ref&cmd=prlinks
Excerpt:
To determine the role of Bartonella species as causes of acute
febrile illness in humans from Thailand, we used a novel strategy
of co-cultivation of blood with eukaryotic cells and subsequent
phylogenetic analysis of Bartonella-specific DNA products.
Bartonella species were identified in 14 blood clots from febrile
patients. Sequence analysis showed that more than one-half of the
genotypes identified in human patients were similar or identical
to homologous sequences identified in rodents from Asia and were
closely related to B. elizabethae, B. rattimassiliensis, and B.
tribocorum. The remaining genotypes belonged to B. henselae, B.
vinsonii, and B. tamiae. Among the positive febrile patients,
animal exposure was common: 36% reported owning either dogs or
cats and 71% reported rat exposure during the 2 weeks before
illness onset. The findings suggest that rodents are likely
reservoirs for a substantial portion of cases of human Bartonella
infections in Thailand.
By Linda on May 20, 2010 in Infections | comments(0)
Abstract:
Bartonella vinsonii subsp. berkhoffii, Bartonella henselae or DNA of both organisms was amplified and sequenced from blood, enrichment blood cultures or autopsy tissues from four family members. Historical and microbiological results support perinatal transmission of Bartonella species in this family.
By Linda on Mar 31, 2010 in Infections | comments(0)
Cat scratch disease is the most common zoonotic infection caused by Bartonella bacteria. Among the many mammals infected with Bartonella spp., cats represent a large reservoir for human infection, as they are the main reservoir for Bartonella henselae, Bartonella clarridgeiae and Bartonella koehlerae. Bartonella spp. are vector-borne bacteria, and transmission of B. henselae by cat fleas occurs mainly through infected flea faeces, although new potential vectors (ticks and biting flies) have been identified. Dogs are also infected with various Bartonella species and share with humans many of the clinical signs induced by these infections. Although the role of dogs as source of human infection is not yet clearly established, they represent epidemiological sentinels for human exposure. Present knowledge on the aetiology, clinical features and epidemiological characteristics of bartonellosis is presented.
