All Posts Tagged With: "cranial neuropathies"

Full article: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20666055&retmode=ref&cmd=prlinks

Excerpt:

Lyme disease is a multisystem infectious disease, endemic in
parts of Europe, including the West of Ireland. Neurological
manifestions (neuroborreliosis) are variable. Presenting
neurological syndromes include meningitis, cranial neuropathies,
myeloradiculitis and mononeuritis multiplex. A lack of
specificity in serological diagnosis may add to diagnostic
confusion. We reviewed thirty cases of acute Lyme disease in the
West of Ireland and found neurological syndromes in 15 (50%),
with painful radiculopathy (12 patients; 80%) and cranial
neuropathy (7 patients; 46%) occurring frequently.
Neuroborreliosis needs to be considered in the differential
diagnosis of these neurological syndromes in the appropriate
clinical context.

Full article: http://jnnp.bmj.com/content/78/12/1409.extract

Excerpt:

Retrobulbar optic neuritis (RON) is an unusual complication of Lyme disease. The diagnosis of early Lyme disease is difficult, and the relationship between RON and Lyme disease remains controversial. None of the 14 cases of optic neuritis described in the literature in association with Lyme disease fulfilled the Halperin and Sibony criteria for active Lyme disease. We report the first case of acute Lyme disease complicated by RON established using the Halperin and Sibony criteria.

Lyme disease is a multisystem infectious disease caused by tick borne spirochetes of the Borrelia burgdorferi group. Diagnosis of this infection can be difficult and serological testing such as western blot can be useful. Cranial neuropathies are common but RON has been reported in a few isolated cases.1 A causal link between optic neuritis and Lyme disease has not been established and remains controversial. We report a case of active neuro-Lyme disease complicated by RON