Tick-borne encephalitis (TBE) in a 6 week old infant
By Linda on Jul 7, 2010 in Infections | comments(0)
Full article: https://www.thieme-connect.com/ejournals/abstract/neuropediatrics/doi/10.1055/s-2004-819478
Excerpt:
Case report: A 6-week-old girl developed fever, irritability, meningeal signs with bulging fontanelle and a partial, secondary-generalized seizure. CSF yielded pleocytosis (172 lymphocytes, 81 mono-cytes/ul) and elevated protein (0,83g/l), cranial MRI showed encephalitic signs in both frontal and parietal lobes. Because of a tick bite in an endemic area 10 days before admission, ELISA-IgG and IgM to TBE-virus were sought and found in serum, whereas Borrelia burgdorferi serology, Herpes-simplex virus PCR and bacterial CSF-culture were negative. Phenobarbitone was administered because of repetitive seizures, while the EEG showed series of sharp waves in the right parieto-temporal region. She consecutively became seizure free. At first follow-up after 6 weeks she demonstrated pathologic neurological signs with increased muscular tone, hyperreflexia, fidgety movements, and EEG showed slow waves in the right parieto-temporal region.
