All Posts Tagged With: "gangliosides"

Excerpt:

RESULTS: Antibodies were detected in all evaluated groups. In
group of neuroborreliosis (lymphocytic meningitis with cranial
nerve invoIvement) there was no essential difference with control
group.
It was stated in group of forestry workers with serological
features of infection B. burgdorferi lasting for years.
CONCLUSIONS: Results of the study do
not support the thesis of participation of IgG autoantibodies
against gangliosides in pathogenesis early disseminated Lyme
borreliosis in form of lymphocytic meningitis with cranial nerves
paresis. Antibodies against endogenous glicosfingolipides in Lyme
borreliosis probably can lead to affecting nervous system
(demielinisation and polineuropathy) but probably require
long-term immunization, what is suggested by results of examined
group of patients with the multi-annual serological features of
infection.