Linda’s comment:  Ok so some may respond to antibiotics, where does the tatigue, joint pain and cognitive dysfunction come from….While IDSA says there is no such thing as chronic Lyme or post treatment LD, this very report speaks of them…..

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21305487&retmode=ref&cmd=prlinks

Excerpt:

Conclusions: In an appropriate clinical setting,
evaluation for POTS in patients suffering from post LD syndrome may lead to
early recognition and treatment, with subsequent improvement in symptoms of
orthostatic intolerance. (Cardiol J 2011; 18, 1: 63-66).

Linda’s comment:  FINALLY a doctor that gets it…..

Excerpt:

Today, clinicians have major concerns with Toxic Body Burden, consisting of toxic heavy metals, pesticides, volatile organic compounds (VOC’s) and pathogen load, and how these poisons adversely affect the nutritional status of their patients. A particularly critical example of the interference of toxins with nutritional status and biochemical function is the competitive aspect of Mercury and Magnesium.     

Mercury, Magnesium and Adenosine triphosphate (ATP)

Mercury specifically competes with Magnesium and interferes with all Magnesium-dependent metabolic pathways, such as production of energy from ATP and GTP, which directly leads to lack of chemical energy. Every cell in the body requires chemical energy derived from ATP or GTP to function, heal and regenerate. Adenosine-5′-triphosphate (ATP) is a multifunctional nucleotide that is critical as the “molecular currency” of intracellular energy transfer. In this role, ATP transports chemical energy within cells for metabolism. It is produced as an energy source during the processes of photosynthesis and cellular respiration and consumed by many enzymes and a multitude of cellular processes, including biosynthetic reactions, motility and cell division. In signal transduction pathways, ATP is used as a substrate by kinases that phosphorylate proteins and lipids, as well as by adenylate cyclase, which uses ATP to produce the second messenger molecule cyclic AMP. If Mercury is present, this cannot occur.

Link: http://www.ncbi.nlm.nih.gov/pubmed/21305487

Excerpt:

Results: Five patients (all women), aged 22-44 years, were identified 
for inclusion in this study. These patients developed symptoms of 
fatigue, cognitive dysfunction, orthostatic palpitations and either near 
syncope or frank syncope. The debilitating nature of these symptoms had 
resulted in lost of the employment or inability to attend school. Three 
patients were also suffering from migraine, two from anxiety and 
depression and one from hypertension. All patients demonstrated a good 
response to the employed treatment. Four of the five were able to engage 
in their activities of daily living and either resumed employment or 
returned to school.

Conclusions: In an appropriate clinical setting, evaluation for POTS in 
patients suffering from post LD syndrome may lead to early recognition 
and treatment, with subsequent improvement in symptoms of orthostatic 
intolerance. (Cardiol J 2011; 18, 1: 63-66).