All Posts Tagged With: "TNF"

Inflammation Linked to Increased Cognitive Decline in Alzheimer’s Disease

It would have been nice to test these patients for environmental toxins and also to see how high their heavy metals were??  Simple way to regulate and determine if metal toxicity has an effect on the cognitive decline?

Perhaps someday the conventional docs will get on the band wagon with the alternative world and begin searching for the “cause” and stop treating symptoms??!!

Angel Huggzz

Linda

Inflammation Linked to Increased Cognitive Decline in Alzheimer’s Disease
Susan Jeffrey
 
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Dr. Daniel Mikol discusses the findings from the multicenter REGARD study.Click here.September 11, 2009 — A new study finds a link between systemic inflammation and increased cognitive decline in patients with established Alzheimer’s disease (AD).
 
In this study, both acute and chronic inflammation, which were in turn associated with increased serum levels of proinflammatory cytokine tumor necrosis factor α (TNF-α), were associated with an increase in the rate of cognitive decline in patients with mild to severe AD.
“The role of TNF-α within the brain is controversial, with evidence supportive of both deleterious and protective effects,” the authors, led by Clive Holmes, MRCPsych, PhD, from the University of Southampton, United Kingdom, conclude. “However, if systemic inflammation has different [central nervous system] consequences depending on the existing relative activation state of the central innate immune system, dampening down systemic TNF-α may prove to be beneficial in AD.”
Their report is published in the September 8 issue of Neurology.
 
Inflammation and Cognitive Decline Continued