All Posts Tagged With: "Ehrlichia canis"

ELISA Lyme test evaluation for Lyme & Co-infections

Link: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21117995&retmode=ref&cmd=prlinks

Excerpt:

Results-Sensitivity and specificity of the in-clinic ELISA for detection of
heartworm antigen (99.2% and 100%, respectively), antibodies against B
burgdorferi (98.8% and 100%, respectively), and antibodies against E canis
(96.2% and 100%, respectively) were similar to results for a similar
commercial ELISA. In samples obtained from dogs in the northeast and upper
Midwest of the United States, sensitivity and specificity of the in-clinic
ELISA for antibodies against Anaplasma spp were 99.1% and 100%,
respectively, compared with results for an immunofluorescence assay. Samples
from 2 dogs experimentally infected with the NY18 strain of A
phagocytophilum were tested by use of the in-clinic ELISA, and antibodies
against A phagocytophilum were detected by 8 days after inoculation.
Antibodies against Anaplasma platys in experimentally infected dogs
cross-reacted with the A phagocytophilum analyte. Coinfections were
identified in several of the canine serum samples.Ā 
Conclusions and Clinical Relevance-
The commercially available in-clinic ELISA could be used by veterinarians to
screen dogs for heartworm infection and for exposure to tick-borne
pathogens.

The increasing recognition of rickettsial pathogens – dogs and people

Full article: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20207197&retmode=ref&cmd=prlinks

Excerpt:

Dogs and people are exposed to and susceptible to infection by
many of the same tick-borne bacterial pathogens in the order
Rickettsiales, including Anaplasma phagocytophilum, Ehrlichia
canis, E. chaffeensis, E. ewingii, Rickettsia rickettsii, R.
conorii, and other spotted fever group rickettsiae. Recent
findings include descriptions of novel Ehrlichia and Rickettsia
species, recognition of the occurrence and clinical significance
of co-infection, and increasing awareness of Rhipicephalus
sanguineus-associated diseases. Newer molecular assays are
available, although renewed efforts to encourage their use are
needed. This review highlights the ecology and epidemiology of
these diseases, and proposes avenues for future investigation.
Published by Elsevier Ltd.