All Posts Tagged With: "plasma cells"

Follicular Borreliosis: An Atypical Presentation of Erythema Chronicum Migrans

Full article: http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000209229

Excerpt:

Lyme serology was positive for both IgG and IgM (ELISA, Enzygnost
Borreliosis , Siemens, Dade Behring, Germany, and blot,
Euroline WB , Euroimmun, Germany). A punch biopsy of a papule showed a dermal perifollicular ( fig. 2 ) – and occasionnally perineural – infiltrate of lymphocytes and plasma cells, consistent with a borrelial infection. Borrelia burgdorferi DNA was amplified from fresh tissue obtained from a skin biopsy performed on a peripilar papule, using a specific real-time PCR according to Mäkinen et al. [1] (culture not performed). The erythema resolved after a 3-week doxycycline treatment whereas arthralgia and dysesthesia persisted.

Spirochetes in cardiac biopsies

Linda’s comment:  This report was posted in 1989 but it still is true today.  Many of us Lymies have/had Lyme Carditis.  It can be frightening to say the least.  I was never one to do antibiotics, but I did plenty of anti microbial’s, herbals, supplements and later the FIGHT lifelong daily detox and don’t have those problems today.  Reducing heavy metals and reducing my total body burden of pathogens and toxins has been God sent to me.  You don’t have to use the brands that I chose, but I know the products I used worked, and are still working for me.   I have battled (5) Cancers, (2) Lyme infections, COPD, Arthritis, CHF, Varestrongylus Klapowi worm, and several other health woes, however once I woke up and made the right lifestyle changes, the battles I fought became much easier.  Giving up GMO foods, removing all the toxins,chemicals, pesticides, herbicides, and toxic cleaning supplies from my home made this healing and detox journey much easier. Being a southern cook, it wasn’t as hard as I anticipated to make cooking changes.  My recipes have become just as delicious.  Did I complain when making these changes, you betcha I did.  However, when I begin my research on all the no no’s in my life and finding out the Cancers were environmental Cancers, threw me right into the mission of making changes.  Once I stopped complaining to my self it was much easier.  It became a challenge to prove to myself I could make these changes.  In the beginning I never told my family that they were eating gluten free or Buffalo meat.  When they began to tell me that they knew something was different, but it tasted good to them, I finally admitted about the gluten free and Buffalo. Regards, Linda

Cardiac involvement occurring early in Borrelia burgdorferi infection is a clinical manifestation of human Lyme disease. Therefore, two patients with acute complete atrioventricular heart blocks and unexplained recurrent dizziness were studied. Both patients had significantly elevated serum titers of IgM and IgG antibodies to B. burgdorferi. Right ventricular subendocardial biopsies showed dense infiltrates consisting of lymphocytes and plasma cells. Silver staining revealed spirochetes characteristic of B. burgdorferi near and in the infiltrates, between the muscle fibers, and in the endocardium. One patient responded to penicillin; the other did not, necessitating installation of a pacemaker. Thus, permanent heart damage may result from cardiac involvement in Lyme disease. Continued